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特布他林、沙丁胺醇和肾上腺素皮下注射治疗儿童急性哮喘发作的比较。

Comparison of subcutaneous injections of terbutaline, salbutamol and adrenaline in acute asthmatic attacks in children.

作者信息

Phanichyakarn P

出版信息

J Med Assoc Thai. 1989 Dec;72(12):692-6.

PMID:2628537
Abstract

Bronchodilating and cardiovascular effects of subcutaneously administered terbutaline, adrenaline 0.01 mg/kg and salbutamol 0.007 mg/kg were compared in a randomized single-blind manner. All drugs produced bronchodilation within 2 minutes and maintained it for 4 hours with terbutaline and adrenaline and for 3 hours with salbutamol. Bronchodilatation elicited by terbutaline was the highest. Increases in heart rate were observed in all especially during the first 30 minutes. All drugs elicited small increases in systolic blood pressure and it was highest with terbutaline from 5 to 240 minutes. Decreases in diastolic blood pressure were observed with all three. Increases in respiratory rate were small and observed within the first 5 to 30 minutes.

摘要

以随机单盲方式比较了皮下注射特布他林、0.01mg/kg肾上腺素和0.007mg/kg沙丁胺醇的支气管扩张作用和心血管效应。所有药物均在2分钟内产生支气管扩张,并维持4小时(特布他林和肾上腺素)或3小时(沙丁胺醇)。特布他林引起的支气管扩张程度最高。所有药物均观察到心率增加,尤其是在最初30分钟内。所有药物均引起收缩压小幅升高,特布他林在5至240分钟时升高幅度最大。三种药物均观察到舒张压降低。呼吸频率增加幅度较小,在最初5至30分钟内观察到。

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1
Comparison of subcutaneous injections of terbutaline, salbutamol and adrenaline in acute asthmatic attacks in children.特布他林、沙丁胺醇和肾上腺素皮下注射治疗儿童急性哮喘发作的比较。
J Med Assoc Thai. 1989 Dec;72(12):692-6.
2
A comparison of the effects of subcutaneous orciprenaline, salbutamol and terbutaline in asthmatic children.皮下注射奥西那林、沙丁胺醇和特布他林对哮喘儿童疗效的比较。
Ann Clin Res. 1974 Apr;6(2):99-104.
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A comparative study of aerosolized terbutaline and subcutaneously administered epinephrine in the treatment of acute bronchial asthma.雾化吸入特布他林与皮下注射肾上腺素治疗急性支气管哮喘的对比研究
Ann Allergy. 1984 Aug;53(2):131-4.
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Adrenaline and terbutaline in treatment of acute asthmatic attacks on children.
J Med Assoc Thai. 1981 Sep;64(9):428-31.
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[Treatment of acute crises of bronchial asthma in children using subcutaneous salbutamol as an alternative to adrenaline: comparative study].
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Comparison of subcutaneous salbutamol and terbutaline with adrenaline.皮下注射沙丁胺醇、特布他林与肾上腺素的比较。
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Comparison of nebulized terbutaline (TERB) and subcutaneous epinephrine (EPI) in the treatment of acute asthma.雾化吸入特布他林(TERB)与皮下注射肾上腺素(EPI)治疗急性哮喘的比较。
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Comparison of subcutaneous terbutaline with epinephrine in the treatment of asthma in children.
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[Subcutaneous adrenaline versus inhaled salbutamol in the treatment of childhood asthmatic crisis].皮下注射肾上腺素与吸入沙丁胺醇治疗儿童哮喘危象的比较
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引用本文的文献

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Comparison of the effects of salbutamol and adrenaline on airway smooth muscle contractility in vitro and on bronchial reactivity in vivo.沙丁胺醇与肾上腺素对体外气道平滑肌收缩性及体内支气管反应性影响的比较。
Thorax. 1994 Nov;49(11):1103-8. doi: 10.1136/thx.49.11.1103.