Donadi E A, Carvalho I F, Falcão R P
Department of Clinical Medicine, School of Medicine, University of São Paulo, Ribeirão Preto, Brazil.
J Clin Lab Immunol. 1989 Apr;28(4):183-5.
A polyethylene-glycol insoluble serum fraction was studied in patients with sickle cell anaemia during the steady state of the disease. The levels of C1q-precipitins were normal but increased amounts of proteins, IgM C3 and factor B were detected in this immune complex enriched serum fraction. These findings are a sign that circulating immune complexes can be detected even in the asymptomatic period of the disease.
在镰状细胞贫血患者疾病稳定期，对一种聚乙二醇不溶性血清组分进行了研究。C1q沉淀素水平正常，但在这种富含免疫复合物的血清组分中检测到蛋白质、IgM、C3和B因子含量增加。这些发现表明，即使在疾病无症状期也可检测到循环免疫复合物。
