Kaiser Permanente, Department of Dermatology, Sacramento, CA, U.S.A.
Stanford University, Department of Pathology, Department of Dermatology, Stanford, CA, U.S.A.
Br J Dermatol. 2016 Feb;174(2):398-401. doi: 10.1111/bjd.14089. Epub 2015 Nov 17.
Plasmablastic lymphoma (PBL) is an unusual subtype of non-Hodgkin lymphoma recently classified as a diffuse immunoblastic lymphoma with a plasma-cell immunophenotype. Originally described in the oral cavity of HIV-positive patients, it has also been recognized to occur rarely at other sites. We describe a previously unreported fistulizing presentation of Epstein-Barr virus (EBV)-positive PBL, reviewing its association with HIV-1 infection and its importance as an AIDS-defining malignancy.
浆母细胞淋巴瘤（PBL）是一种非霍奇金淋巴瘤的罕见亚型，最近被归类为具有浆细胞免疫表型的弥漫性免疫母细胞淋巴瘤。最初在 HIV 阳性患者的口腔中描述，也已被认识到在其他部位罕见发生。我们描述了一例以前未报道的伴有 EBV 阳性的 PBL 的瘘管形成表现，回顾了其与 HIV-1 感染的关联及其作为艾滋病定义性恶性肿瘤的重要性。
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