Weill Cornell Medical College, Massachusetts General Hospital, 1300 York Avenue, New York, NY, 10021, USA.
Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Bartlett Hall 6R, Boston, MA, 02114, USA.
Am J Clin Dermatol. 2019 Jun;20(3):423-442. doi: 10.1007/s40257-019-00422-0.
Antiretroviral therapy (ART) has revolutionized the treatment and prognosis of people living with HIV (PLHIV). With increased survival and improved overall health, PLHIV are experiencing dermatologic issues both specific to HIV and common to the general population. In this new era of ART, it is crucial for dermatologists to have a strong understanding of the broad range of cutaneous disease and treatment options in this unique population. In this review, we outline the most common skin diseases in PLHIV, including HIV-associated malignancies, inflammatory conditions, and infections, and focus on the role of ART in altering epidemiology, clinical features, diagnosis, and treatment of cutaneous conditions.
抗逆转录病毒疗法 (ART) 彻底改变了人类免疫缺陷病毒 (HIV) 感染者 (PLHIV) 的治疗和预后。随着生存时间的延长和整体健康状况的改善，PLHIV 同时出现了 HIV 特有的和普通人群共有的皮肤科问题。在这个 ART 的新时代，皮肤科医生必须深入了解这一特殊人群中广泛的皮肤疾病和治疗选择。在这篇综述中，我们概述了 PLHIV 中最常见的皮肤疾病，包括与 HIV 相关的恶性肿瘤、炎症性疾病和感染，并重点介绍了 ART 在改变皮肤疾病的流行病学、临床特征、诊断和治疗方面的作用。
