Weber P, Meluzinova H, Matejovska-Kubesova H, Polcarova V, Jarkovsky J, Bielakova K, Weberova D
Bratisl Lek Listy. 2015;116(7):408-16. doi: 10.4149/bll_2015_078.
With advancing age, the degree of dependency and occurrence of great geriatric syndromes (GS), also referred to as geriatric giants, grow substantially.
The prospective cohort study was aimed at conducting an analysis and comparison of geriatric syndromes (geriatric giants) among different age groups at admission to the acute geriatric department.
SETTING, PARTICIPANTS: Between 1995 and 2012, we had altogether 12,210 elderly patients at an average age of 80.5 ± 7.0 y (range 65-103 y) hospitalised at the Department of Geriatrics. We divided the patient set into three different age subgroups (65-74 y; 75-84 y and ≥85 y; e.g. 21.4%; 47.9% and 30.7%) and compared the results among them.
3,787 persons (31.0%) were without any GS. The growing tendency of the occurrence of all geriatric syndromes in combinations with increased age (p<0.001) is obvious. Their occurrence in the above mentioned different age sets was examined in relation to individual geriatric syndromes and sex (female and male), namely falls 22.0%, 27.8%, 39.9% and 20.5%, 27.0%, 36.1%; immobility 26.4%, 29.3%, 42.5% and 30.3%, 30.1% and 39.2%; incontinence 38.4%, 50.6%, 69.5% and 38.2%, 47.4%, 61.8 %; dementia and cognitive impairment 13.4%, 23.4%, 38.1% and 15.8%, 24.3%, 33.2% respectively. Age cut-off for geriatric syndromes occurrence based on ROC analysis is 83.5-84.5 y for females and 78.5-82.5 y for males.
The occurrence of geriatric giants increasing with age and female gender is of crucial importance not only for individuals and families but also for demands on costs of health and social care in oncoming decades (Tab. 6, Fig. 3, Ref. 52).
随着年龄增长,依赖程度以及重大老年综合征(GS,也称为老年巨症)的发生率大幅上升。
前瞻性队列研究旨在对老年急性科收治的不同年龄组的老年综合征(老年巨症)进行分析和比较。
地点、参与者:1995年至2012年期间,我们共有12210名老年患者在老年医学科住院,平均年龄为80.5±7.0岁(范围65 - 103岁)。我们将患者分为三个不同年龄亚组(65 - 74岁;75 - 84岁和≥85岁;例如21.4%、47.9%和30.7%)并比较了组间结果。
3787人(31.0%)无任何老年综合征。所有老年综合征的发生率随年龄增长呈上升趋势(p<0.001),这一趋势很明显。针对上述不同年龄组,我们考察了个体老年综合征以及性别(女性和男性)与老年综合征发生情况的关系,即跌倒发生率分别为22.0%、27.8%、39.9%以及20.5%、27.0%、36.1%;活动障碍发生率分别为26.4%、29.3%、42.5%以及30.3%、30.1%、39.2%;失禁发生率分别为38.4%、50.6%、69.5%以及38.2%、47.4%、61.8%;痴呆和认知障碍发生率分别为13.4%、23.4%、38.1%以及15.8%、24.3%、33.2%。基于ROC分析,女性老年综合征发生的年龄切点为83.5 - 84.5岁,男性为78.5 - 82.5岁。
老年巨症的发生率随年龄和女性性别增加,这不仅对个人和家庭至关重要,而且对未来几十年的医疗保健和社会护理成本需求也至关重要(表6,图3,参考文献52)。