Department of Rheumatology, Hospital of Southern Norway Trust Kristiansand,
Department of Rheumatology, Hospital of Southern Norway Trust Kristiansand, Department of Neuroscience, Division of Rheumatology, Norwegian University of Science and Technology, Trondheim and.
Rheumatology (Oxford). 2016 Jan;55(1):66-70. doi: 10.1093/rheumatology/kev289. Epub 2015 Aug 18.
Permanent visual impairment has been reported to occur in up to 19% of GCA patients. The aim of this study was to examine whether implementation of a fast-track approach could reduce the rate of permanent visual impairment and inpatient days of care in GCA patients.
A fast-track outpatient GCA clinic (FTC) was implemented in the Department of Rheumatology, Hospital of Southern Norway Trust Kristiansand, Norway in 2012. The patients included in this study were subsequently recruited between March 2010 and October 2014. Routine clinical and laboratory data and number of inpatient days of care were collected.
During the observation period, 75 patients were diagnosed with GCA. Among the 75 GCA patients, 32 were evaluated conventionally and 43 in the FTC. In the conventionally approached group, six patients suffered from permanent visual impairment, while in the FTC group only one patient suffered from permanent visual impairment. The relative risk of permanent visual impairment in the GCA patients examined in the FTC was 88% lower compared with the conventionally evaluated group (relative risk 0.12, 95% CI: 0.01, 0.97, P = 0.01). The mean difference in inpatient days of care between patients evaluated conventionally and patients evaluated in the FTC was 3 days (3.6 vs 0.6 days, P < 0.0005).
The implementation of the FTC in GCA care appears to significantly reduce the risk of permanent visual impairment and is more cost effective by reducing the need for inpatient care.
据报道,高达 19%的巨细胞动脉炎(GCA)患者会出现永久性视力障碍。本研究旨在探讨快速通道管理方案的实施是否可以降低 GCA 患者永久性视力障碍的发生率和住院天数。
2012 年,挪威南森特兰郡信托克里斯蒂安桑医院的风湿病科实施了快速通道门诊 GCA 门诊(FTC)。本研究纳入的患者于 2010 年 3 月至 2014 年 10 月期间招募。收集常规临床和实验室数据以及住院天数。
在观察期间,75 例患者被诊断为 GCA。75 例 GCA 患者中,32 例采用常规方法评估,43 例采用 FTC 评估。在常规治疗组中,6 例患者出现永久性视力障碍,而在 FTC 组中仅 1 例患者出现永久性视力障碍。与常规评估组相比,在 FTC 中接受检查的 GCA 患者发生永久性视力障碍的相对风险降低了 88%(相对风险 0.12,95%CI:0.01,0.97,P=0.01)。常规评估组和 FTC 评估组患者的住院天数差异为 3 天(3.6 天与 0.6 天,P<0.0005)。
在 GCA 护理中实施 FTC 似乎可以显著降低永久性视力障碍的风险,并通过减少住院需求而更具成本效益。