Levin O S
Russian Medical Academy Postgraduate Education, Moscow.
Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(4):83-87. doi: 10.17116/jnevro20151154183-87.
Buspirone, a nonbenzodiasepine anxiolytic, is a partial serotonin 5-HT1A-receptor agonist, D2-autoreceptor antagonist and low affinity 5-HT2-receptor agonist. This medication is used for treatment of generalized anxiety disorder though it may be prescribed in other anxiety states, primarily, panic disorder, sociophobia and depression. Buspirone seems to be potential in treatment of other neurological and mental disorders (tardive dyskinesia in Parkinson's disease, ataxia, behavioral disorders, cranial/brain injuries, dementia, attention-deficit hyperactivity disorder).
丁螺环酮是一种非苯二氮䓬类抗焦虑药，是一种5-羟色胺5-HT1A受体部分激动剂、D2自身受体拮抗剂和低亲和力5-HT2受体激动剂。这种药物用于治疗广泛性焦虑症，不过它也可能被开用于其他焦虑状态，主要是恐慌症、社交恐惧症和抑郁症。丁螺环酮在治疗其他神经和精神障碍（帕金森病的迟发性运动障碍、共济失调、行为障碍、颅脑损伤、痴呆、注意力缺陷多动障碍）方面似乎具有潜力。
