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皮肤异色性淀粉样变:一种罕见的网状色素沉着性皮肤病。

Amyloidosis Cutis Dyschromica: A Rare Reticulate Pigmentary Dermatosis.

作者信息

Verma Shyam, Joshi Rajiv

机构信息

Department of Dermatology, P.D. Hinduja Hospital, Mumbai, Maharashtra, India.

出版信息

Indian J Dermatol. 2015 Jul-Aug;60(4):385-7. doi: 10.4103/0019-5154.160491.

Abstract

We are reporting a rare case of amyloidosis cutis dyschromica in a 41-year-old man. This is a rare form of primary cutaneous amyloidosis characterized by reticulate pigmentation with hypopigmented and hyperpigmented macules, onset in childhood, familial tendency in some, occasional mild itching and deposition of amyloid in the papillary dermis. Our case also had multiple bilaterally symmetrical hyperpigmented keratotic papules abutting the axillary vault resembling those seen in Dowling-Deogs disease. The other unusual feature in this patient was the strong family history of vitiligo, which we are unable to explain. We have also tried to explain the mechanism leading to the hyperpigmentation and hypopigmentation in amyloidosis cutis dyschromica.

摘要

我们报告了一例41岁男性的罕见的皮肤异色性淀粉样变病例。这是一种罕见的原发性皮肤淀粉样变,其特征为网状色素沉着,伴有色素减退和色素沉着斑,发病于儿童期,部分病例有家族倾向,偶有轻度瘙痒,淀粉样蛋白沉积于乳头真皮层。我们的病例还出现了多个双侧对称的色素沉着性角化丘疹,毗邻腋窝穹窿,类似于Dowling-Deogs病所见。该患者的另一个不寻常特征是有白癜风的家族病史,我们无法对此作出解释。我们还试图解释皮肤异色性淀粉样变中色素沉着和色素减退的发生机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1b9b/4533539/cce86372f6be/IJD-60-385-g001.jpg

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本文引用的文献

1
Amyloidosis cutis dyschromica.皮肤异色性淀粉样变病。
Indian Dermatol Online J. 2013 Oct;4(4):344-6. doi: 10.4103/2229-5178.120678.
2
Amyloidosis cutis dyschromica.异色性皮肤淀粉样变。
Orphanet J Rare Dis. 2012 Dec 12;7:95. doi: 10.1186/1750-1172-7-95.
3
Amyloidosis cutis dyschromica: a rare pigmentary disorder.皮肤异色性淀粉样变:一种罕见的色素沉着障碍。
J Cutan Pathol. 2011 Oct;38(10):823-6. doi: 10.1111/j.1600-0560.2011.01701.x. Epub 2011 May 19.
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A rare type of primary cutaneous amyloidosis: amyloidosis cutis dyschromica.
Int J Dermatol. 2010 Dec;49(12):1416-8. doi: 10.1111/j.1365-4632.2009.04394.x.

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