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短肠综合征与吸收不良——病因与预防

Short Bowel Syndrome and Malabsorption - Causes and Prevention.

作者信息

Thompson Jon S

机构信息

Department of Surgery, University of Nebraska Medical Center, Omaha, NE, USA.

出版信息

Viszeralmedizin. 2014 Jun;30(3):174-8. doi: 10.1159/000363276.

DOI:10.1159/000363276
PMID:26288591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4513821/
Abstract

BACKGROUND

The short bowel syndrome (SBS) is a condition caused by extensive intestinal resection for a variety of conditions. The etiology varies by age group. Necrotizing enterocolitis is the leading cause in infants. In older children, trauma and malignancies are most common. Postoperative SBS has become most common in adults, followed by mesenteric vascular disease and cancer/irradiation.

METHODS

Systematic literature review.

RESULTS

Prevention of SBS should be given high priority. Each of the etiologies has been evaluated and strategies to prevent extensive resection have been developed. These include a thoughtful approach to reoperation, early identification of complications, e.g. intestinal ischemia, reducing radiation enteritis, and bowel-conserving therapies in diseases such as Crohn's disease.

CONCLUSION

Several operative strategies to prevent SBS are useful. Timing and extent of reoperation need careful consideration. Minimizing intestinal resection, bowel-conserving techniques for complications such as fistula or strictures, and remodeling procedures are important.

摘要

背景

短肠综合征(SBS)是由于各种原因进行广泛肠切除所致的一种病症。其病因因年龄组而异。坏死性小肠结肠炎是婴儿的主要病因。在大龄儿童中,创伤和恶性肿瘤最为常见。术后短肠综合征在成人中最为常见,其次是肠系膜血管疾病和癌症/放疗。

方法

系统文献综述。

结果

应高度重视短肠综合征的预防。已对每种病因进行了评估,并制定了预防广泛切除的策略。这些策略包括对再次手术的审慎处理、早期识别并发症(如肠缺血)、减少放射性肠炎以及对克罗恩病等疾病采用保留肠段的治疗方法。

结论

几种预防短肠综合征的手术策略是有用的。再次手术的时机和范围需要仔细考虑。尽量减少肠切除、针对瘘管或狭窄等并发症采用保留肠段的技术以及重塑手术很重要。

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本文引用的文献

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Short bowel syndrome after laparoscopic procedures.腹腔镜手术后的短肠综合征
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2
Surgical treatment of intra-abdominal desmoid tumors resulting in short bowel syndrome.手术治疗导致短肠综合征的腹腔内韧带样瘤。
Cancers (Basel). 2012 Jan 19;4(1):31-8. doi: 10.3390/cancers4010031.
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Impact of complete mesenteric closure on small bowel obstruction and internal mesenteric hernia after laparoscopic Roux-en-Y gastric bypass.完全肠系膜封闭对腹腔镜 Roux-en-Y 胃旁路术后小肠梗阻和内肠系膜疝的影响。
Surg Obes Relat Dis. 2013 Nov-Dec;9(6):850-4. doi: 10.1016/j.soard.2012.11.007. Epub 2013 Jan 17.
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Long-term outcome after extensive intestinal resection for chronic radiation enteritis.广泛肠切除术治疗慢性放射性肠炎的长期结果。
Dig Liver Dis. 2013 Feb;45(2):110-4. doi: 10.1016/j.dld.2012.10.003. Epub 2012 Nov 11.
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A study on 107 patients with acute mesenteric ischemia over 30 years.一项对 30 多年来 107 例急性肠系膜缺血患者的研究。
Int J Surg. 2012;10(9):510-3. doi: 10.1016/j.ijsu.2012.07.011. Epub 2012 Aug 7.
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Risk factors for short bowel syndrome in patients with Crohn's disease.克罗恩病患者短肠综合征的风险因素。
Surg Today. 2012 May;42(5):447-52. doi: 10.1007/s00595-011-0098-0. Epub 2011 Dec 17.
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Morbidity and mortality after bowel resection for acute mesenteric ischemia.急性肠系膜缺血性肠切除术后的发病率和死亡率。
Surgery. 2011 Oct;150(4):779-87. doi: 10.1016/j.surg.2011.07.079.
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Enterocutaneous fistulas and a hostile abdomen: reoperative surgical approaches.肠外瘘和敌对的腹部:再次手术的方法。
World J Surg. 2012 Mar;36(3):516-23. doi: 10.1007/s00268-011-1306-1.
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Crohn's disease patients with chronic intestinal failure receiving long-term parenteral nutrition: a cross-national adult study.克罗恩病慢性肠衰竭患者接受长期肠外营养:一项跨国成人研究。
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