Rahimi Alireza, Haghighi Mohammad, Shamsaei Farshid
Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, IR Iran.
Iran J Psychiatry Behav Sci. 2015 Jun;9(2):e1116. doi: 10.17795/ijpbs1116. Epub 2015 Jun 1.
Obsessive-compulsive disorder (OCD) is a psychiatric disorder, which has been shown to affect 2 - 3.5% of people, during their lifetimes. Identification of familial more homogenous characteristics of OCD may help to define relevant subtypes and increase the power of genetic and neurobiological studies of OCD.
This case report describes an adult woman suffering from symptoms of energy loss, insomnia, lack of appetite, and depressed mood. The patient history was positive for counting coercion. The patient's genogram revealed counting coercion in three generations of her family.
This case highlights the issue whether counting can be a distinctive feature among inflicted and not inflicted individuals, such as hoarding. Also, it is still unclear what is it really transferred; the vulnerability to disease, which is transferred among three generations, or the symptoms of counting itself, by genes. Further studies are required to answer the debates on this issue.
强迫症(OCD)是一种精神疾病,已证实在人们的一生中会影响2%至3.5%的人群。确定强迫症在家族中更具同质性的特征,可能有助于定义相关亚型,并提高强迫症基因和神经生物学研究的效力。
本病例报告描述了一名成年女性,她出现了精力丧失、失眠、食欲不振和情绪低落等症状。患者病史显示有计数强迫症状呈阳性。患者的系谱图显示其家族三代人都有计数强迫症状。
本病例突出了一个问题,即计数是否会像囤积一样,成为患病和未患病个体之间的一个显著特征。此外,目前仍不清楚真正传递的是什么:是三代人之间传递的疾病易感性,还是通过基因传递的计数症状本身。需要进一步的研究来回答关于这个问题的争论。