Kamiński A, Gede K, Owsińska H
Przegl Dermatol. 1989 May-Jun;76(3):256-61.
Potassium penicillin G was administered intravenously 4 times daily in doses of 6 million u for 10 days to 49 patients, 36 with central nervous system syphilis and 13 with latent seroresistant syphilis. Forty six patients were followed up after treatment. In 16 patients with central nervous system syphilis treated by this method another cerebrospinal fluid examination was done. Cerebrospinal fluid changes regressed completely in 13 patients, in three cases the improvement was incomplete. The titres of VDRL and FTA tests decreased in 23 patients with central nervous system syphilis and in 11 with latent seroresistant syphilis. In eight patients treated by this method seroresistance persisted and in four cases the titre fluctuated. The results of the study demonstrate the effectiveness and advantages of the treatment of central nervous system syphilis and latent seroresistant syphilis with crystalline penicillin administered intravenously.
对49例患者静脉注射钾青霉素G，每日4次，剂量为600万单位，持续10天，其中36例患有中枢神经系统梅毒，13例患有潜伏性血清抵抗性梅毒。46例患者治疗后进行了随访。对16例采用该方法治疗的中枢神经系统梅毒患者进行了另一次脑脊液检查。13例患者的脑脊液变化完全消退，3例改善不完全。23例中枢神经系统梅毒患者和11例潜伏性血清抵抗性梅毒患者的VDRL和FTA试验滴度下降。8例采用该方法治疗的患者血清抵抗持续存在，4例滴度波动。研究结果表明，静脉注射结晶青霉素治疗中枢神经系统梅毒和潜伏性血清抵抗性梅毒有效且具有优势。
