Coetzee André Joannou, Castro Eumenia, Peres Luiz Cesar
a Department of Histopathology , Sheffield Children's Hospital , Western Bank , United Kingdom.
b Department of Pathology and Immunology , Texas Childrens Hospital , Houston , Texas , USA.
Fetal Pediatr Pathol. 2015;34(5):336-9. doi: 10.3109/15513815.2015.1075634. Epub 2015 Aug 20.
The aim of this study was to analyze abnormalities of umbilical coiling index (UCI) in twin gestation to test whether the coiling is genetically influenced by zygosity.
Data retrieved comprised gestational age (GA), chorionicity, fetal gender, and UCI.
The mean UCI of hypercoiled cords in monochorionic placentas was 0.55 coils/cm and 0.49 coils/cm in dichorionic placentas with discordant fetal gender (P = 0.2629).
In conclusion, no significant statistical difference between UCI in monochorionic and dichorionic twin placentas with discordant fetal gender was identified, suggesting that zygosity does not play a role in umbilical coiling induction.
本研究的目的是分析双胎妊娠中脐动脉卷曲指数(UCI)的异常情况,以检验卷曲是否受合子性的遗传影响。
检索的数据包括孕周(GA)、绒毛膜性、胎儿性别和UCI。
单绒毛膜胎盘中超卷曲脐带的平均UCI在双绒毛膜胎盘且胎儿性别不一致时分别为0.55圈/厘米和0.49圈/厘米(P = 0.2629)。
总之,在单绒毛膜和双绒毛膜双胎胎盘且胎儿性别不一致时,UCI之间未发现显著统计学差异,这表明合子性在脐动脉卷曲诱导中不起作用。