复发性耐甲氧西林金黄色葡萄球菌皮肤脓肿与洗必泰使用期间洗必泰敏感性降低的选择
Recurrent Methicillin-Resistant Staphylococcus aureus Cutaneous Abscesses and Selection of Reduced Chlorhexidine Susceptibility during Chlorhexidine Use.
作者信息
Johnson Ryan C, Schlett Carey D, Crawford Katrina, Lanier Jeffrey B, Merrell D Scott, Ellis Michael W
机构信息
Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
Infectious Diseases Clinical Research Program, Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA.
出版信息
J Clin Microbiol. 2015 Nov;53(11):3677-82. doi: 10.1128/JCM.01771-15. Epub 2015 Aug 19.
Abstract
We describe the selection of reduced chlorhexidine susceptibility during chlorhexidine use in a patient with two episodes of cutaneous USA300 methicillin-resistant Staphylococcus aureus abscess. The second clinical isolate harbors a novel plasmid that encodes the QacA efflux pump. Greater use of chlorhexidine for disease prevention warrants surveillance for resistance.
摘要
我们描述了在一名患有两例皮肤美国300型耐甲氧西林金黄色葡萄球菌脓肿的患者使用洗必泰期间出现洗必泰敏感性降低的情况。第二株临床分离株携带一种编码QacA外排泵的新型质粒。更多地使用洗必泰预防疾病需要对耐药性进行监测。
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