[Various defense factors of gastroduodenal mucosa in different time periods after suturing ulcer perforation].

Perforation of ulcer occurred after distinct impairments in protective mechanisms of gastric mucosal membrane; this suggestion was corroborated by studies of glycoprotein content in blood serum of patients with perforating gastroduodenal ulcer within the early postoperation period. Studies of the glycoprotein in blood serum and urine within the later periods after the operation showed that the mucosal protective barrier was completely restored in some patients, thus protecting against the ulcer exacerbation, while recurrence of the disease was observed in the patients with deteriorated protective mechanisms in gastric mucosal membrane.