治疗肌萎缩侧索硬化症和亨廷顿舞蹈症潜在靶点概述
An Overview of Potential Targets for Treating Amyotrophic Lateral Sclerosis and Huntington's Disease.
作者信息
de Paula Caroline Zocatelli, Gonçalves Bruno Daniel Correia, Vieira Luciene Bruno
机构信息
Laboratório de Neurofarmacologia, Departamento de Farmacologia, Instituto de Ciências Biológicas (ICB), Universidade Federal de Minas Gerais, Campus Pampulha, 31270901 Belo Horizonte, MG, Brazil.
出版信息
Biomed Res Int. 2015;2015:198612. doi: 10.1155/2015/198612. Epub 2015 Jul 29.
Abstract
Neurodegenerative diseases affect millions of people worldwide. Progressive damage or loss of neurons, neurodegeneration, has severe consequences on the mental and physical health of a patient. Despite all efforts by scientific community, there is currently no cure or manner to slow degeneration progression. We review some treatments that attempt to prevent the progress of some of major neurodegenerative diseases: Amyotrophic Lateral Sclerosis and Huntington's disease.
摘要
神经退行性疾病影响着全球数百万人。神经元的渐进性损伤或丧失，即神经退行性变，会对患者的身心健康造成严重后果。尽管科学界做出了种种努力，但目前尚无治愈方法或减缓退行性变进程的方式。我们回顾了一些试图阻止某些主要神经退行性疾病进展的治疗方法：肌萎缩侧索硬化症和亨廷顿舞蹈症。
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