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草莓海螺(Strombus luhuanus)鳃下腺中一种高分子量毒素的检测及其某些特性

Detection and some properties of a high molecular weight toxin in the hypobranchial gland of strawberry conch Strombus luhuanus.

作者信息

Abiko Keisuke, Iwayama Ayane, Shiomi Kazuo

机构信息

Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan-4, Minato-ku, Tokyo 108-8477, Japan.

Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan-4, Minato-ku, Tokyo 108-8477, Japan.

出版信息

Toxicon. 2015 Oct;105:1-3. doi: 10.1016/j.toxicon.2015.08.011. Epub 2015 Aug 20.

DOI:10.1016/j.toxicon.2015.08.011
PMID:26299337
Abstract

The extract from the hypobranchial gland of strawberry conch Strombus luhuanus was found to be lethal to mice. There were no marked regional and seasonal variations in toxicity although a considerable individual variation was recognized. The toxin was thermostable and extractable with aqueous solvents but not with organic solvents. Behaviors in dialysis, ultrafiltration and column chromatography on various adsorbents suggested that the toxin is a high molecular weight acidic substance of 400-500 k.

摘要

已发现草莓海螺(Strombus luhuanus)鳃下腺提取物对小鼠具有致死性。尽管存在相当大的个体差异,但在毒性方面没有明显的区域和季节变化。该毒素具有热稳定性,可用水性溶剂提取,但不能用有机溶剂提取。在透析、超滤以及在各种吸附剂上进行柱色谱分析时的表现表明,该毒素是一种分子量为400 - 500k的高分子量酸性物质。

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