Suppr超能文献

提高儿科风湿病患者的肺炎球菌疫苗接种率。

Improving Pneumococcal Vaccination in Pediatric Rheumatology Patients.

出版信息

Pediatrics. 2015 Sep;136(3):e681-6. doi: 10.1542/peds.2014-2512.

Abstract

BACKGROUND AND OBJECTIVE

Many pediatric rheumatology patients are at increased risk of pneumococcal disease secondary to a deficient immune system and/or immunosuppressive medications. The goal of this study was to improve pneumococcal vaccination rates in this high-risk population.

METHODS

Eligible patients included children at least 2 years old and adults with systemic lupus erythematosus and/or currently on immunosuppressive medication. Interventions included a presentation to rheumatology providers,creation of immunization algorithm, previsit planning, placing reminders on clinic forms, and sending reminder e-mails to providers. Chart reviews were performed, and control charts were established to portray change in immunization rates.

RESULTS

The preintervention immunization rates for 90 patient visits compared with the immunization rates for the 53-week postintervention period with 1033 patient visits and 299 separate patients were all statistically significant.The 13-valent pneumococcal conjugate vaccine rate increased from 6.7% to48.4% (x2 = 58.3, P , .001), 23-valent pneumococcal polysaccharide vaccinerate increased from 8.9% to 28.4% (x2 = 16.0, P , .001), and combined rate increased from 0% to 23.2% (x2 = 25.2, P , .001). The improvement was sustained with shifts in the data for each vaccine and combined immunizations for final average rates of 60.9% for 13-valent pneumococcal conjugate vaccine, 39.2% for 23-valent pneumococcal polysaccharide vaccine,and 33.7% for combined.

CONCLUSIONS

Pneumococcal vaccination is an important part of the care for systemic lupus erythematosus patients and patients on immunosuppressive medications. Simple interventions through this quality improvement project led to a marked increase in pneumococcal vaccination rates in this vulnerable population.

摘要

背景与目的

许多儿科风湿病患者由于免疫系统缺陷和/或免疫抑制药物而处于罹患肺炎球菌病的高风险中。本研究旨在提高该高危人群的肺炎球菌疫苗接种率。

方法

符合条件的患者包括至少 2 岁的儿童和患有系统性红斑狼疮和/或目前正在接受免疫抑制药物治疗的成年人。干预措施包括向风湿病医生进行演示、制定免疫接种算法、就诊前规划、在诊所表格上放置提醒、向医生发送提醒电子邮件。进行了病历回顾,并建立控制图以描述免疫接种率的变化。

结果

90 次就诊的干预前免疫接种率与 1033 次就诊和 299 位患者的 53 周干预后免疫接种率相比,均具有统计学意义。13 价肺炎球菌结合疫苗接种率从 6.7%增加到 48.4%(x2 = 58.3,P ,.001),23 价肺炎球菌多糖疫苗接种率从 8.9%增加到 28.4%(x2 = 16.0,P ,.001),合并接种率从 0%增加到 23.2%(x2 = 25.2,P ,.001)。随着每种疫苗和联合免疫接种数据的变化,最终平均接种率分别为 13 价肺炎球菌结合疫苗 60.9%、23 价肺炎球菌多糖疫苗 39.2%和联合疫苗 33.7%,这种改善得以维持。

结论

肺炎球菌疫苗接种是系统性红斑狼疮患者和接受免疫抑制药物治疗的患者治疗的重要组成部分。通过本质量改进项目的简单干预措施,使该脆弱人群的肺炎球菌疫苗接种率显著提高。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验