Garas J, Stravolemos K, Athanasiou E, Fassoulaki A
Int Surg. 1979 Nov-Dec;64(6):55-7.
Forty-three patients (two males and 41 females) were submitted to bilateral adrenalectomy for disseminated mammary carcinoma. Several factors were considered for their prognostic value in predicting the response to endocrine ablation. The age of the patients, the treatment of the primary lesion, the free interval, the location of metastases and the involvement of regional lymph nodes did not affect the response to adrenalectomy. Response to therapeutic castration was directly correlated to the response to adrenalectomy (P less than 0.01); this is a valuable predicting factor that should be taken into consideration before proceeding to bilateral adrenalectomy. A statistically significant variation in survival between the responders and nonresponders was found (P less than 0.05). Finally, the high response rate to the operation (53.4%) can be attributed to the complete removal of the adrenal tissue during the operation.
43例患者（2例男性，41例女性）因弥漫性乳腺癌接受了双侧肾上腺切除术。对若干因素在预测内分泌消融反应中的预后价值进行了考量。患者的年龄、原发灶的治疗情况、无瘤间期、转移部位及区域淋巴结受累情况均不影响对肾上腺切除术的反应。治疗性去势反应与肾上腺切除术反应直接相关（P<0.01）；这是一个有价值的预测因素，在进行双侧肾上腺切除术之前应予以考虑。在反应者与无反应者之间发现了生存方面具有统计学意义的差异（P<0.05）。最后，手术的高反应率（53.4%）可归因于手术过程中肾上腺组织的完全切除。
