Janelli D E, Monteleone F, Mishrick A, Kashiwabara H
Int Surg. 1979 May-Jul;64(4):27-31.
Of 135 patients who had bilateral adrenalectomies for metastatic breast cancer, 110 could be evaluated and 63 patients (57.3%) responded (43 objective, 20 subjective responders). Patients aged 31 to 45 years had a 56% response rate; 58% of patients aged 46 to 70 responded. Oophorectomy responders benefited from adrenalectomy 62% of the time and oophorectomy failures reponded in 38% of the cases. Patients with a disease-free interval of zero to 2.5 years responded to adrenalectomy at a rate of 46%, whereas patients with a free interval greater than 2.5 years responded at a rate of 73%. The median survival rate of 63 adrenalectomy responders was 28 months; it was ten months for 47 nonresponders.
在135例因转移性乳腺癌接受双侧肾上腺切除术的患者中，110例可进行评估，63例患者（57.3%）有反应（43例客观反应者，20例主观反应者）。年龄在31至45岁的患者反应率为56%；46至70岁的患者中有58%有反应。接受卵巢切除术且有反应的患者62%从肾上腺切除术中获益，而接受卵巢切除术但未产生效果的患者有38%对肾上腺切除术有反应。无病间期为0至2.5年的患者对肾上腺切除术的反应率为46%，而无病间期大于2.5年的患者反应率为73%。63例肾上腺切除术有反应患者的中位生存期为28个月；47例无反应患者的中位生存期为10个月。
