Zakaria S, el-Raziky E H, el-Kalouby A H, Shaker Z A, Hunter S, Ata A A, el-Battawy Y
Egypt J Bilharz. 1979;6(1-2):11-19.
The study included 916 schistosomal patients and 97 controls. The prevalence of HBs-Ag and anti-HBs was significantly higher in the bilharzial patients compared to controls. Their frequency was higher in the ascitic than the hepatosplenic group, and the difference between each and the simple group was highly significant. Cases with current jaundice showed highly significant frequency of both HBs-Ag and anti-HBs compared to those with no history or manifest jaundice at the time of study. In addition, cases with raised bilirubin, SGPT and SGOT showed significantly higher frequency of HBs-Ag and anti-HBs compared to cases having normal levels. On the other hand, the frequency was not affected by the level of serum alkaline phosphatases. As regards liver pathology, cases with mixed pathologic picture showed significantly higher frequency of both HBs-Ag an anti-HBs compared with those having pure schistosomal lesions.
该研究纳入了916例血吸虫病患者和97名对照。与对照组相比，血吸虫病患者中乙肝表面抗原（HBs-Ag）和乙肝表面抗体（抗-HBs）的患病率显著更高。其在腹水组中的频率高于肝脾组，且腹水组和肝脾组与单纯组之间的差异高度显著。与研究时无黄疸病史或无明显黄疸的患者相比，当前有黄疸的患者中HBs-Ag和抗-HBs的频率均高度显著。此外，胆红素、谷丙转氨酶（SGPT）和谷草转氨酶（SGOT）升高的患者中HBs-Ag和抗-HBs的频率显著高于水平正常的患者。另一方面，该频率不受血清碱性磷酸酶水平的影响。至于肝脏病理学，具有混合病理表现的患者中HBs-Ag和抗-HBs的频率均显著高于仅有单纯血吸虫病病变的患者。
