Suppr超能文献

环尾狐猴(Lemur catta)的孤立性骨软骨瘤

Solitary Osteochondroma in a Ring-Tailed Lemur (Lemur catta).

作者信息

Hope Katharine L, Boedeker Nancy C, Gordon Sebastian S, Walsh Timothy F

机构信息

Wildlife Health Sciences, Smithsonian's National Zoological Park, Washington, District of Columbia, USA.

North Hobart Veterinary Hospital, North Hobart, Tasmania, Australia.

出版信息

Comp Med. 2015 Aug;65(4):348-51.

Abstract

A 20-y-old, male, ring-tailed lemur (Lemur catta) presented with a large, firm mass on the proximal caudolateral left femur. The animal displayed no clinical signs associated with the mass. Radiographs revealed a mineralized mass protruding from the femur, with an intact femoral cortex. Histopathology diagnosed osteochondroma in view of the presence of a peripheral layer of cartilage with progressive endochondral ossification and typical remodeling of bony trabeculae. The mass grew quickly after the initial biopsy, and a second surgery to debulk 95% of the tumor was performed. Histopathologic features of the larger samples were similar to those of the initial biopsies, with the cartilage layer being discontinuous and development of bone from some borders progressing directly from a periost-like layer. Nineteen months after the second surgery, the mass had regrown and extended further proximally on the femur toward the epiphysis, but the animal remained asymptomatic, and additional debulking was not attempted. This report is the first description of an osteochondroma in a prosimian and describes unique behavior of the tumor compared with osteochondromas found in humans, dogs, and cats.

摘要

一只20岁的雄性环尾狐猴(Lemur catta)左侧股骨近端后外侧出现一个大的、质地坚硬的肿块。该动物未表现出与肿块相关的临床症状。X线片显示有一个矿化肿块从股骨突出,股骨皮质完整。鉴于存在一层外周软骨,伴有进行性软骨内成骨和典型的骨小梁重塑,组织病理学诊断为骨软骨瘤。初次活检后肿块迅速生长,遂进行了第二次手术,切除了95%的肿瘤。较大样本的组织病理学特征与初次活检相似,软骨层不连续,部分边界处的骨形成直接从类似骨膜的层开始。第二次手术后19个月,肿块复发并在股骨上进一步向近端延伸至骨骺,但该动物仍无症状,未尝试再次减瘤。本报告首次描述了原猴亚目动物中的骨软骨瘤,并描述了该肿瘤与人类、犬类和猫类骨软骨瘤相比的独特行为。

相似文献

本文引用的文献

2
Extraskeletal osteochondroma on a cat´s elbow.猫肘部的骨外骨软骨瘤。
J S Afr Vet Assoc. 2012 Sep 10;83(1):104. doi: 10.4102/jsava.v83i1.104.
7
Multiple osteochondromas.多发性骨软骨瘤
Orphanet J Rare Dis. 2008 Feb 13;3:3. doi: 10.1186/1750-1172-3-3.
8
A newly recognized pattern of canine osteochondromatosis.一种新发现的犬骨软骨瘤病模式。
Vet Radiol Ultrasound. 2002 Mar-Apr;43(2):132-7. doi: 10.1111/j.1740-8261.2002.tb01660.x.
9
Malignant transformation of solitary spinal osteochondroma in two mature dogs.
Vet Radiol Ultrasound. 1999 Nov-Dec;40(6):634-7. doi: 10.1111/j.1740-8261.1999.tb00891.x.
10
Thoracolumbar vertebral osteochondroma in a young dog.
J Am Vet Med Assoc. 1991 Oct 15;199(8):1054-6.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验