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角膜环植入物的生物力学

Biomechanics of Corneal Ring Implants.

作者信息

Daxer Albert

机构信息

*Gutsehen Eye Center, Ybbs, Austria; and †Department of Ophthalmology, Medical University of Innsbruck, Innsbruck, Austria.

出版信息

Cornea. 2015 Nov;34(11):1493-8. doi: 10.1097/ICO.0000000000000591.

Abstract

PURPOSE

To evaluate the biomechanics of corneal ring implants by providing a related mathematical theory and biomechanical model for the treatment of myopia and keratoconus.

METHODS

The spherical dome model considers the inhomogeneity of the tunica of the eye, dimensions of the cornea, lamellar structure of the corneal stroma, and asphericity of the cornea. It is used in this study for calculating a strengthening factor sf for the characterization of different ring-shaped corneal implant designs. The strengthening factor is a measure of the amount of strengthening of the cornea induced by the implant.

RESULTS

For ring segments and incomplete rings, sf = 1.0, which indicates that these implants are not able to strengthen the cornea. The intracorneal continuous complete ring (MyoRing) has a strengthening factor of up to sf = 3.2. The MyoRing is, therefore, able to strengthen the cornea significantly.

CONCLUSIONS

The result of the presented biomechanical analysis of different ring-shaped corneal implant designs can explain the different postoperative clinical results of different implant types in myopia and keratoconus.

摘要

目的

通过提供相关数学理论和生物力学模型,用于治疗近视和圆锥角膜,评估角膜环植入物的生物力学。

方法

球形穹顶模型考虑了眼球膜的不均匀性、角膜尺寸、角膜基质的板层结构以及角膜的非球面性。本研究中使用该模型计算强化因子sf,以表征不同环形角膜植入物设计。强化因子是植入物引起的角膜强化量的一种度量。

结果

对于环形节段和不完整环,sf = 1.0,这表明这些植入物无法强化角膜。角膜内连续完整环(MyoRing)的强化因子高达sf = 3.2。因此,MyoRing能够显著强化角膜。

结论

对不同环形角膜植入物设计进行的生物力学分析结果,可以解释不同植入物类型在近视和圆锥角膜治疗中不同的术后临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ca7/4598073/f056bef6b467/cornea-34-1493-g001.jpg

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