Eye Specialist Center, Manama, Kingdom of Bahrain.
J Refract Surg. 2011 Jan;27(1):63-8. doi: 10.3928/1081597X-20100212-11. Epub 2010 Feb 15.
to evaluate the refractive and visual results of a new treatment for keratoconus using the corneal intrastromal implantation system (CISIS).
six eyes of four patients with keratoconus were treated with CISIS. Follow-up was 1, 3, and 6 months. After creating an intracorneal pocket of 9-mm diameter and 300-microm depth, a flexible full-ring implant was inserted via a 4-mm-wide corneal tunnel.
no eyes showed loss of lines in uncorrected distance visual acuity (UDVA) or spectacle corrected distance visual acuity (CDVA) at any follow-up examination. Uncorrected and distance corrected visual acuity, keratometry, spherical and cylindrical refractive error as well as spherical equivalent refraction improved significantly (P<.05). Mean UDVA improved from 20/260 to 20/48 and mean CDVA improved from 20/41 to 20/27. A significant centralization and decrease of the corneal apex was found. No intra- or postoperative complications were observed.
the corneal intrastromal implantation system using a complete ring implanted in a stromal pocket can achieve significant improvements in the visual function of patients with keratoconus. Uncorrected distance visual acuity improved by more than seven lines on average and CDVA improved by two lines.
评估使用角膜基质内植入系统（CISIS）治疗圆锥角膜的新疗法的屈光和视觉效果。
对 4 名圆锥角膜患者的 6 只眼采用 CISIS 进行治疗。随访时间为 1、3 和 6 个月。在创建直径为 9 毫米且深度为 300 微米的角膜基质内口袋后，通过 4 毫米宽的角膜隧道插入柔性全环植入物。
在任何随访检查中，均未发现未矫正的远视力（UDVA）或矫正后的远视力（CDVA）损失。未矫正和距离矫正的视力、角膜曲率计、球镜和柱镜屈光不正以及等效球镜屈光均有显著改善（P<.05）。UDVA 平均值从 20/260 提高到 20/48，CDVA 平均值从 20/41 提高到 20/27。发现角膜顶点显著中心化和变平。未观察到术中或术后并发症。
使用完整环植入基质袋的角膜基质内植入系统可显著改善圆锥角膜患者的视觉功能。未矫正的远视力平均提高了 7 行以上，CDVA 提高了 2 行。
