Andrade Solange Dourado de, Andrade Maria Graciede Filha Santarém, Santos Pablo José, Galvão Maria de Lourdes, Barros Mariana Martins de, Ramasawmy Rajendranath, Safe Izabella Picinin, Monteiro Wuelton Marcelo, Sabidó Meritxell, Alecrim Maria das Graças Costa
Fundação de Medicina Tropical Doutor Heitor Vieira Dourado, Manaus, Amazonas, BR.
Rev Soc Bras Med Trop. 2015 Jul-Aug;48(4):498-500. doi: 10.1590/0037-8682-0314-2014.
Here, we describe a case of acute disseminated encephalomyelitis (ADEM) that occurred during a plausible risk interval following inactivated influenza vaccination in a previously healthy 27-year-old man from Manaus, Brazil. He was treated with intravenous methylprednisolone and immunoglobulin. One-month follow-up revealed resolution of the brain lesions, but not of the spinal cord lesions. No recurrence or progression of the main neurological symptoms was observed. After two years of monitoring, the patient continues to experience weak lower limbs and urinary retention. Thus, we recommend that ADEM should be considered in a patient presenting with neurological symptoms after influenza vaccination.
在此，我们描述了一例急性播散性脑脊髓炎（ADEM）病例，该病例发生在一名来自巴西玛瑙斯的27岁既往健康男性接种灭活流感疫苗后的一个合理风险期内。他接受了静脉注射甲泼尼龙和免疫球蛋白治疗。1个月的随访显示脑部病变消退，但脊髓病变未消退。未观察到主要神经症状的复发或进展。经过两年的监测，患者仍持续存在下肢无力和尿潴留。因此，我们建议对于接种流感疫苗后出现神经症状的患者应考虑ADEM。
