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日本青少年幽门螺杆菌感染的筛查、识别与根除

Screening to Identify and Eradicate Helicobacter pylori Infection in Teenagers in Japan.

作者信息

Akamatsu Taiji, Okamura Takuma, Iwaya Yugo, Suga Tomoaki

机构信息

Endoscopy Center, Suzaka Prefectural Hospital, Nagano Prefectural Hospital Organization, 1332 Suzaka, Suzaka, Nagano 382-0091, Japan; Gastroenterology, Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

Gastroenterology, Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

出版信息

Gastroenterol Clin North Am. 2015 Sep;44(3):667-76. doi: 10.1016/j.gtc.2015.05.008. Epub 2015 Jun 19.

DOI:10.1016/j.gtc.2015.05.008
PMID:26314676
Abstract

The purpose of this study was to elucidate the prevalence and effect of Helicobacter pylori infection in Japanese teenagers. The study subjects were students ages 16 to 17 from one high school studied between 2007 and 2013. Students who tested positive on this screening examination underwent esophagogastroduodenoscopy and biopsy samples to determine their H pylori status using culture and histology. Cure of H pylori infections was determined by urea breath test. The low rate of prevalence of H pylori infection in present Japanese teenagers makes it possible and cost effective to perform examinations and carry out treatment of this infection in nationwide health screenings of high school students.

摘要

本研究的目的是阐明幽门螺杆菌感染在日本青少年中的流行情况及其影响。研究对象为2007年至2013年期间对一所高中16至17岁的学生。在此次筛查中检测呈阳性的学生接受了食管胃十二指肠镜检查,并采集活检样本,通过培养和组织学检查来确定其幽门螺杆菌感染状况。幽门螺杆菌感染的治愈情况通过尿素呼气试验来判定。目前日本青少年中幽门螺杆菌感染率较低,这使得在全国范围内对高中生进行健康筛查时开展该感染的检查和治疗成为可能且具有成本效益。

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