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[表面生物活性陶瓷(初步报告)]

[Surface bioactive ceramics (preliminary report)].

作者信息

Urban K, Strnad Z, Spohrová D

出版信息

Acta Chir Orthop Traumatol Cech. 1989 Oct;56(5):391-7.

PMID:2631487
Abstract

The Research and Development Institute of Industrial Glass in the town of Teplice (North Bohemia) has developed bioceramics (BAS-O) with presupposed surface activity manifested during its implantation in the macroorganism. The test was carried out by means of Macor inert ceramics produced by Corning Co. In total there were performed 8 implantations of surface active bioceramics and 7 implantations of inert ceramics in the tibiae and femurs of four dogs. After two months the experimental animals were sacrificed and the implants were examined. All eight prisms of BAS-O surface active ceramics were firmly connected with the bone and could be removed from bones only by force. On the contrary, the control inert ceramics could be removed from the bone by a pincette. The contact X-ray pictures showed an interface of surrounding tissue around inert ceramics and contrary to this, in case of surface bioceramics the bone trabeculea penetrated into the implants. The surrounding fibrous tissue around inert ceramics was proved in all cases by microscopic examination. In case of surface active bioceramics the fibrous intermedial layer was not proved even by electron microscopy.

摘要

位于捷克共和国北波希米亚州特普利采镇的工业玻璃研发机构开发出了一种生物陶瓷(BAS - O),其预设的表面活性在植入大型生物体过程中得以体现。该测试借助康宁公司生产的Macor惰性陶瓷进行。总共在四只狗的胫骨和股骨中进行了8次表面活性生物陶瓷植入以及7次惰性陶瓷植入。两个月后,处死实验动物并对植入物进行检查。所有8个BAS - O表面活性陶瓷棱柱都与骨头紧密相连,只能通过用力才能从骨头中取出。相反,对照的惰性陶瓷能用镊子从骨头中取出。接触式X光片显示了惰性陶瓷周围组织的界面,与此相反,对于表面生物陶瓷,骨小梁侵入了植入物。通过显微镜检查,在所有情况下都证实了惰性陶瓷周围存在纤维组织。而对于表面活性生物陶瓷,即使通过电子显微镜检查也未证实存在纤维中间层。

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