MSA：一个用于多序列比对的R软件包。
msa: an R package for multiple sequence alignment.
作者信息
Bodenhofer Ulrich, Bonatesta Enrico, Horejš-Kainrath Christoph, Hochreiter Sepp
机构信息
Institute of Bioinformatics, Johannes Kepler University, Linz, Austria.
出版信息
Bioinformatics. 2015 Dec 15;31(24):3997-9. doi: 10.1093/bioinformatics/btv494. Epub 2015 Aug 26.
UNLABELLED
Although the R platform and the add-on packages of the Bioconductor project are widely used in bioinformatics, the standard task of multiple sequence alignment has been neglected so far. The msa package, for the first time, provides a unified R interface to the popular multiple sequence alignment algorithms ClustalW, ClustalOmega and MUSCLE. The package requires no additional software and runs on all major platforms. Moreover, the msa package provides an R interface to the powerful package shade which allows for flexible and customizable plotting of multiple sequence alignments.
AVAILABILITY AND IMPLEMENTATION
msa is available via the Bioconductor project: http://bioconductor.org/packages/release/bioc/html/msa.html. Further information and the R code of the example presented in this paper are available at http://www.bioinf.jku.at/software/msa/.
未标注
尽管R平台和生物导体项目的附加软件包在生物信息学中被广泛使用，但到目前为止，多序列比对的标准任务一直被忽视。msa软件包首次为流行的多序列比对算法ClustalW、ClustalOmega和MUSCLE提供了统一的R接口。该软件包无需额外的软件，可在所有主流平台上运行。此外，msa软件包为功能强大的shade软件包提供了R接口，该软件包允许对多序列比对进行灵活且可定制的绘图。
可用性和实现方式
msa可通过生物导体项目获取：http://bioconductor.org/packages/release/bioc/html/msa.html。本文中示例的更多信息和R代码可在http://www.bioinf.jku.at/software/msa/获取。
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