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急性脑梗死患者睡眠障碍的研究

Research of Sleep Disorders in Patients with Acute Cerebral Infarction.

作者信息

Chen Xiaofang, Bi Hongye, Zhang Meiyun, Liu Haiyan, Wang Xueying, Zu Ruonan

机构信息

Department of Neurology, Tianjin Union Medicine Centre, Tianjin, China.

Department of Neurology, Tianjin Union Medicine Centre, Tianjin, China.

出版信息

J Stroke Cerebrovasc Dis. 2015 Nov;24(11):2508-13. doi: 10.1016/j.jstrokecerebrovasdis.2015.06.033. Epub 2015 Aug 24.

DOI:10.1016/j.jstrokecerebrovasdis.2015.06.033
PMID:26316356
Abstract

BACKGROUND

The purpose of this study is to investigate the incidence of sleep disorders (SD), characteristic of cerebral infarction patients with different parts affected.

METHODS

The research selected 101 patients with a first occurrence of acute cerebral infarction as the experimental group, and 86 patients without cerebral infarction as controls. Polysomnography, Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and US National Stroke Scale were assessed.

RESULTS

Compared with control group, the incidence of SD was higher in experimental group (P < .05), and the incidence of SD in women was more frequent in experimental group (P < .05). There was no significant difference in the types of SD patients with acute cerebral infarction. In addition, the sleep quality of cerebral infarction patients with different parts affected was different: the sleep quality of left hemisphere infarction patients was poor compared with the right one, and the sleep quality of anterior circulation patients was poor compared with posterior circulation patients. Patients with thalamus infarction had a longer sleep time and a shorter sleep latency and stage 2 of non-rapid eye movement sleep compared with non-thalamus infarction group.

CONCLUSIONS

The prevalence of SD was relatively high in acute cerebral infarction patients, and the detailed classification of acute cerebral infarction may provide a more effective therapeutic method and therefore relieve patients' pain and supply a better quality of sleep.

摘要

背景

本研究旨在调查睡眠障碍(SD)的发生率,以及不同部位脑梗死患者的特征。

方法

本研究选取101例首次发生急性脑梗死的患者作为实验组,86例无脑梗死的患者作为对照组。对两组患者进行多导睡眠图、匹兹堡睡眠质量指数、爱泼华嗜睡量表及美国国立卫生研究院卒中量表评估。

结果

与对照组相比,实验组睡眠障碍发生率更高(P < 0.05),且实验组女性睡眠障碍发生率更高(P < 0.05)。急性脑梗死患者睡眠障碍类型无显著差异。此外,不同部位脑梗死患者的睡眠质量不同:左侧半球梗死患者的睡眠质量比右侧半球梗死患者差,前循环梗死患者的睡眠质量比后循环梗死患者差。与非丘脑梗死组相比,丘脑梗死患者睡眠时间更长,睡眠潜伏期及非快速眼动睡眠2期更短。

结论

急性脑梗死患者睡眠障碍患病率相对较高,急性脑梗死的详细分类可能提供更有效的治疗方法,从而减轻患者痛苦,提高睡眠质量。

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