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CROES肾石测量法作为经皮肾镜取石术结果术前预测系统的外部验证

External Validation of CROES Nephrolithometry as a Preoperative Predictive System for Percutaneous Nephrolithotomy Outcomes.

作者信息

Sfoungaristos Stavros, Gofrit Ofer N, Yutkin Vladimir, Landau Ezekiel H, Pode Dov, Duvdevani Mordechai

机构信息

Department of Urology, Hadassah and Hebrew University Hospital, Jerusalem, Israel.

Department of Urology, Hadassah and Hebrew University Hospital, Jerusalem, Israel.

出版信息

J Urol. 2016 Feb;195(2):372-6. doi: 10.1016/j.juro.2015.08.079. Epub 2015 Aug 24.

Abstract

PURPOSE

We externally validated CROES (Clinical Research Office of the Endourological Society) nephrolithometry and evaluated the predictive accuracy of the nomogram.

MATERIALS AND METHODS

Data were collected on patients who underwent percutaneous nephrolithotomy between January 2012 and February 2015. The CROES nomogram was applied to all patients and externally validated. The AUC and calibration plot were used for discrimination and clinical validity assessment.

RESULTS

A total of 176 patients were included in study. Mean ± SD patient age was 55.2 ± 13.9 years and the mean stone burden was 640.0 ± 911.4 mm(2). The CROES nomogram was significantly associated with stone number, location and burden, and the number of implicated calyces, punctures and tracts. The postoperative treatment success rate was 85.8%. The number of stones, number of implicated calyces and CROES score were independent predictors of treatment success. The estimated AUC was 0.715 and the model provided good calibration.

CONCLUSIONS

The CROES nomogram is an accurate tool to estimate renal stone complexity. CROES nephrolithometry provides great accuracy to predict postoperative efficacy.

摘要

目的

我们对腔内泌尿外科协会临床研究办公室(CROES)的肾结石测量法进行了外部验证,并评估了列线图的预测准确性。

材料与方法

收集2012年1月至2015年2月期间接受经皮肾镜取石术患者的数据。将CROES列线图应用于所有患者并进行外部验证。使用AUC和校准图进行鉴别和临床有效性评估。

结果

共176例患者纳入研究。患者平均年龄±标准差为55.2±13.9岁,平均结石负荷为640.0±911.4 mm²。CROES列线图与结石数量、位置和负荷以及受累肾盏数量、穿刺次数和通道显著相关。术后治疗成功率为85.8%。结石数量、受累肾盏数量和CROES评分是治疗成功的独立预测因素。估计AUC为0.715,该模型具有良好的校准。

结论

CROES列线图是评估肾结石复杂性的准确工具。CROES肾结石测量法在预测术后疗效方面具有很高的准确性。

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