Chen Xing, Peng Pan Xin, He Yu Hui, Ding Zhen Shan, Wang Jian Feng, Tan Yi Wei, Zhou Xiao Feng
Department of Urology,China-Japan Friendship Hospital,Beijing 100029,China.
Teaching and Research Section of Urology,Peking University China-Japan Friendship School of Clinical Medicine,Beijing 100029,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Aug 30;41(4):492-500. doi: 10.3881/j.issn.1000-503X.10767.
To compare the accuracy of SHA.LIN,S.T.O.N.E.nephrolithometry scoring system,and Clinical Research Office of the Endourological Society(CROES)nephrolithometry nomogram in predicting percutaneous nephrolithotomy(PCNL)outcomes including stone free rate(SFR)and perioperative status. Methods The clinical data of 90 patients with nephrolithiasis undergoing PCNL in department of urology,China-Japan Friendship Hospital from January 2015 to March 2018 were retrospectively analyzed.The general data,stone characteristics,operation approaches,and perioperative variables were recorded.SHA.LIN,S.T.O.N.E.score,and CROES nomogram were assigned according to the computed tomography(CT)findings before surgery.Stone free status was evaluated by kidney-ureter-bladder one month after PCNL.The relationships of SHA.LIN score,S.T.O.N.E.score,and CROES score with SFR,postoperative complications,operation time(OT),length of hospital stay(LOS),estimated blood loss(EBL),and decrease of hemoglobin was evaluated.Receiver operating characteristic(ROC)curves were used to analyze the predictive accuracy. Results The SFR was 72.2%(65/90)and postoperative complications occurred in 33 cases(36.7%).The mean OT was(103.1±39.6)min,the mean EBL was(46.1±53.0)ml,the mean LOS was(15.3±5.2)d,the mean postoperative LOS was(8.5±3.4)d,and the mean decrease of hemoglobin was(16.1±10.2)g/L.Stone-free patients had significantly lower SHA.LIN score(8.23 10.36,=0.000)and S.T.O.N.E.score(7.05 8.16,=0.000)and significantly higher CROES score(188.50 143.89,=0.000)compared to patients with residual fragments.All these scores were not significantly associated with complications(>0.05).On the other hand,all these scores were significantly correlated with OT,EBL,and decrease of hemoglobin(SHA.LIN:=0.006,=0.028,=0.014;S.T.O.N.E.:=0.012,=0.047,=0.011;and CROES:=0.040,=0.045,=0.013).SHA.LIN(=0.001)and S.T.O.N.E.(=0.005)scores were associated with LOS.Logistic regression analysis revealed that SHA.LIN(=2.491),S.T.O.N.E.(=3.030),and CROES(=0.973)scores were significantly associated with stone-free status.ROC curves in predicting SFR showed that there was significant difference in the areas under the curves(AUC)for the SHA.LIN S.T.O.N.E.score [0.808(95% =0.711-0.905) 0.748(95% =0.632-0.864),=0.047].AUC for the CROES score [0.770(95% =0.664-0.877)] showed no significantly different for the SHA.LIN score or the S.T.O.N.E.score(>0.05). Conclusions All these three scoring systems have good predictive accuracy for SFR.SHA.LIN is more precise than S.T.O.N.E.in predicting SFR.However,they can not predict postoperative complications.
比较SHA.LIN、S.T.O.N.E.肾结石测量评分系统及腔内泌尿外科临床研究办公室(CROES)肾结石测量列线图预测经皮肾镜取石术(PCNL)结局(包括结石清除率(SFR)和围手术期状况)的准确性。方法回顾性分析2015年1月至2018年3月在中国-日本友好医院泌尿外科接受PCNL的90例肾结石患者的临床资料。记录一般资料、结石特征、手术方式及围手术期变量。术前根据计算机断层扫描(CT)结果计算SHA.LIN、S.T.O.N.E.评分及CROES列线图。PCNL术后1个月通过肾脏-输尿管-膀胱检查评估结石清除状态。评估SHA.LIN评分、S.T.O.N.E.评分及CROES评分与SFR、术后并发症、手术时间(OT)、住院时间(LOS)、估计失血量(EBL)及血红蛋白下降的关系。采用受试者工作特征(ROC)曲线分析预测准确性。结果SFR为72.2%(65/90),33例(36.7%)发生术后并发症。平均OT为(103.1±39.6)分钟,平均EBL为(46.1±53.0)毫升,平均LOS为(15.3±5.2)天,平均术后住院时间为(8.5±3.4)天,平均血红蛋白下降为(16.1±10.2)克/升。与有残余结石碎片的患者相比,结石清除患者的SHA.LIN评分(8.23比10.36,P = 0.000)和S.T.O.N.E.评分(7.05比8.16,P = 0.000)显著更低,CROES评分(188.50比143.89,P = 0.000)显著更高。所有这些评分与并发症均无显著相关性(P>0.05)。另一方面,所有这些评分与OT、EBL及血红蛋白下降均显著相关(SHA.LIN:P = 0.006,P = 0.028,P = 0.014;S.T.O.N.E.:P = 0.012,P = 0.047,P = 0.011;CROES:P = 0.040,P = 0.045,P = 0.013)。SHA.LIN(P = 0.001)和S.T.O.N.E.(P = 0.005)评分与LOS相关。逻辑回归分析显示,SHA.LIN(P = 2.491)、S.T.O.N.E.(P = 3.030)及CROES(P = 0.973)评分与结石清除状态显著相关。预测SFR的ROC曲线显示,SHA.LIN与S.T.O.N.E.评分的曲线下面积(AUC)存在显著差异[0.808(95%CI = 0.711 - 0.905)比0.748(95%CI = 0.632 - 0.864),P = 0.047]。CROES评分的AUC[0.770(95%CI = 0.664 - 0.877)]与SHA.LIN评分或S.T.O.N.E.评分相比无显著差异(P>0.05)。结论这三种评分系统对SFR均有良好的预测准确性。在预测SFR方面,SHA.LIN比S.T.O.N.E.更精确。然而,它们无法预测术后并发症。