Kochutina L N, Klishov A A
Arkh Anat Gistol Embriol. 1989 Nov;97(11):44-52.
Regularities of the skeletal muscle tissue histogenesis have been studied in the canine shin at its elongation by 50% of its initial length by means of the mono- and bilocal distractive osteosynthesis after Ilizarov. Using light and electron microscopy, it has been stated that under conditions of monolocal distractive osteosynthesis, when the strain effort acts in the area of the muscle belly, together with elongation dystrophic and necrotic changes, proliferation of the intermuscular connective tissue and atrophy of myons increase. In a half of a year, after cessation of distraction there is no complete restoration of the skeletal muscle tissue structure. Under conditions of bilocal distractive osteosynthesis, when the conditions of the muscle distortion are comparable to those existing during the period of the extremity growth, cellular type of regeneration in the skeletal muscle tissue predominates. Therefore growth of the muscle fibers is longitudinal, like that of their growth in the process of ontogenesis and the structure of the muscle tissue of the extremity elongated is preserved. The results of the experiment performed demonstrate certain prospectiveness of application of the bilocal distractive osteosynthesis method in practical orthopedics.
通过伊里扎洛夫单部位和双部位牵张成骨术，在犬胫骨伸长至其初始长度的50%时，研究了骨骼肌组织的组织发生规律。利用光学显微镜和电子显微镜观察发现，在单部位牵张成骨条件下，当牵张力作用于肌腹区域时，除了伸长性营养不良和坏死性改变外，肌间结缔组织增生和肌纤维萎缩也会增加。在停止牵张半年后，骨骼肌组织结构并未完全恢复。在双部位牵张成骨条件下，当肌肉变形情况与肢体生长期间的情况相当时，骨骼肌组织中细胞型再生占主导。因此，肌纤维呈纵向生长，就像它们在个体发育过程中的生长一样，并且伸长肢体的肌肉组织结构得以保留。所进行的实验结果表明，双部位牵张成骨术在实际骨科应用中具有一定的前景。
