Mikhaĭlova L N, Shtin V P
Arkh Patol. 1979;41(5):55-64.
Electron microscopic examination of the regenerating tissue was performed after distractional osteosynthesis carried out by the method of G. A. Ilizarov. The results showed osteogenesis to occur on the basis of the fibrous tissue formed in diastasis. The observed zones of the regeneration typical of distractional osteosynthesis are due to functional stimulation (tension) resulting in the arrangement of collagen fiber bundles and bone trabeculae in the direction of the extension forces. Cells of the skeletogenic tissue, between the bone fragments are also arranged with their longitudinal axis along the collagen fibril bundles. The ultrastructural pattern of the osteogenesis after distractional osteosynthesis reflects the intensification of the synthesis of glycosaminoglycan-protein complexes forming the main substance of the bone tissue.
采用G. A. 伊里扎洛夫方法进行牵张成骨术后，对再生组织进行了电子显微镜检查。结果显示，成骨过程是在骨间隙形成的纤维组织基础上发生的。牵张成骨典型的观察到的再生区域是由于功能刺激（张力）导致胶原纤维束和骨小梁沿牵伸力方向排列。骨碎片之间的成骨组织细胞也沿胶原纤维束的纵轴排列。牵张成骨术后成骨的超微结构模式反映了形成骨组织主要物质的糖胺聚糖 - 蛋白质复合物合成的增强。
