钆注射后10分钟和4小时获得的磁共振图像中单侧内耳症状患者内耳对比增强的比较。
Comparison of Inner Ear Contrast Enhancement among Patients with Unilateral Inner Ear Symptoms in MR Images Obtained 10 Minutes and 4 Hours after Gadolinium Injection.
作者信息
Kim T Y, Park D W, Lee Y J, Lee J Y, Lee S H, Chung J H, Lee S
机构信息
From the Departments of Radiology (T.Y.K., D.W.P., S.L.).
From the Departments of Radiology (T.Y.K., D.W.P., S.L.)
出版信息
AJNR Am J Neuroradiol. 2015 Dec;36(12):2367-72. doi: 10.3174/ajnr.A4439. Epub 2015 Aug 27.
BACKGROUND AND PURPOSE
Recently 4-hour delayed-enhanced 3D-FLAIR MR imaging has been used in pathophysiologic analysis of the inner ear in many auditory diseases, including sudden sensorineural hearing loss, but comparison among different time points is not clear in patients with unilateral inner ear symptoms. We compared the signal-intensity ratios of the inner ears in patients with unilateral inner ear symptoms on 10-minute delayed-enhanced and 4-hour delayed-enhanced 3D-FLAIR MR images after IV gadolinium injection.
MATERIALS AND METHODS
The 10-minute delayed-enhanced and 4-hour delayed-enhanced 3D-FLAIR MR images were retrospectively analyzed. Signal-intensity ratios between the cerebellum and inner ear structures, such as the cochleae, vestibules, and vestibulocochlear nerve were assessed. Multiple comparisons were performed.
RESULTS
Signal-intensity ratios of the affected cochleae, vestibules, and vestibulocochlear nerve were higher than those of unaffected sides in both 10-minute delayed-enhanced and 4-hour delayed-enhanced images. At the affected side, signal-intensity ratios of the vestibulocochlear nerve were higher in patients with nonsudden sensorineural hearing loss than in those with sudden sensorineural hearing loss on both 10-minute delayed-enhanced and 4-hour delayed-enhanced images. The signal-intensity ratios of some affected inner ear structures were higher than those of the unaffected sides in a group of 30 patients with sudden sensorineural hearing loss and 20 patients with nonsudden sensorineural hearing loss on 10-minute delayed-enhanced and 4-hour delayed-enhanced images.
CONCLUSIONS
Signal-intensity ratios of the inner ear show statistically significant increases in many diseases, especially neuritis, in 10-minute delayed-enhanced and 4-hour delayed-enhanced images. The 4-hour delayed-enhanced images may be superior in neural inflammatory-dominant conditions, while 10-minute delayed-enhanced images may be superior in neural noninflammatory-dominant conditions.
背景与目的
近来，4小时延迟增强三维液体衰减反转恢复（3D-FLAIR）磁共振成像已被用于多种听觉疾病（包括突发性感音神经性听力损失）内耳的病理生理分析，但单侧内耳症状患者不同时间点的比较尚不清楚。我们比较了静脉注射钆剂后，单侧内耳症状患者在10分钟延迟增强和4小时延迟增强3D-FLAIR磁共振图像上内耳的信号强度比。
材料与方法
回顾性分析10分钟延迟增强和4小时延迟增强3D-FLAIR磁共振图像。评估小脑与内耳结构（如耳蜗、前庭和前庭蜗神经）之间的信号强度比。进行了多重比较。
结果
在10分钟延迟增强和4小时延迟增强图像中，患侧耳蜗、前庭和前庭蜗神经的信号强度比均高于未患侧。在患侧，非突发性感音神经性听力损失患者的前庭蜗神经信号强度比在10分钟延迟增强和4小时延迟增强图像上均高于突发性感音神经性听力损失患者。在一组30例突发性感音神经性听力损失患者和20例非突发性感音神经性听力损失患者中，10分钟延迟增强和4小时延迟增强图像上一些患侧内耳结构的信号强度比高于未患侧。
结论
内耳的信号强度比在许多疾病（尤其是神经炎）中，在10分钟延迟增强和4小时延迟增强图像上有统计学意义的增加。4小时延迟增强图像在以神经炎症为主的情况下可能更具优势，而10分钟延迟增强图像在以神经非炎症为主的情况下可能更具优势。
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