膜脂促进血小板成熟。
Membrane grease eases platelet maturation.
作者信息
Min Sang H, Abrams Charles S
机构信息
UNIVERSITY OF PENNSYLVANIA.
出版信息
Blood. 2015 Aug 27;126(9):1055-6. doi: 10.1182/blood-2015-07-655241.
Abstract
In this issue of Blood, Valet et al1 report a novel regulatory role of class II phosphoinositide 3-kinase (PI3K)-C2α in the morphology and remodeling of platelet membranes and its implications in platelet maturation and arterial thrombosis.
摘要
在本期《血液》杂志中，瓦莱特等人报告了II类磷酸肌醇3激酶（PI3K）-C2α在血小板膜形态和重塑中的一种新的调节作用及其在血小板成熟和动脉血栓形成中的意义。
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本文引用的文献
1
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Blood. 2015 Aug 27;126(9):1128-37. doi: 10.1182/blood-2015-03-636670. Epub 2015 Jun 24.
2
The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function.血小板的 II 类 PI3 激酶，PI3KC2α，将血小板内部膜结构与切变依赖性黏附功能联系起来。
Nat Commun. 2015 Mar 17;6:6535. doi: 10.1038/ncomms7535.
3
Regulation of platelet plug formation by phosphoinositide metabolism.磷酸肌醇代谢调节血小板栓形成。
Blood. 2013 Aug 22;122(8):1358-65. doi: 10.1182/blood-2013-05-427716. Epub 2013 Jun 11.
4
The incredible journey: From megakaryocyte development to platelet formation.从巨核细胞发育到血小板形成：不可思议的旅程。
J Cell Biol. 2013 Jun 10;201(6):785-96. doi: 10.1083/jcb.201304054.
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The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation. spectrin 骨架稳定了小鼠巨核细胞膜系统，对前期血小板和血小板的形成是必需的。
Blood. 2011 Aug 11;118(6):1641-52. doi: 10.1182/blood-2011-01-330688. Epub 2011 May 12.
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Cytoskeletal mechanics of proplatelet maturation and platelet release.原代血小板成熟和血小板释放的细胞骨架力学。
J Cell Biol. 2010 Nov 15;191(4):861-74. doi: 10.1083/jcb.201006102.
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