Bochner Aaron F, Madhivanan Purnima, Niranjankumar Bhavana, Ravi Kavitha, Arun Anjali, Krupp Karl, Klausner Jeffrey D
Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98195, USA.
Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, 11200 SW 8 Street, HLS 390W2, Miami, FL 33199, USA ; Public Health Research Institute of India, Mysore, Karnataka 560020, India.
J Sex Transm Dis. 2013;2013:750415. doi: 10.1155/2013/750415. Epub 2013 Nov 14.
Objectives. To assess the prevalence and determinants of herpes simplex virus type 2 (HSV-2) infections among pregnant women attending mobile antenatal health clinic in rural villages in Mysore Taluk, India. Methods. Between January and September 2009, 487 women from 52 villages participated in this study. Each participant consented to provide a blood sample for HSV-2 and HIV testing and underwent an interviewer-administered questionnaire. Results. HSV-2 prevalence was 6.7% (95% confidence interval (CI) 4.4-9.0), and one woman tested positive for HIV. The median age of women was 20 years and 99% of women reported having a single lifetime sex partner. Women whose sex partner traveled away from home had 2.68 (CI: 1.13-6.34) times the odds of being HSV-2 seropositive compared to women whose sex partner did not travel. Having experienced genital lesions was also associated with HSV-2 infection (P value = 0.08). Conclusion. The 6.7% HSV-2 prevalence was similar to results obtained in studies among pregnant women in other parts of India. It appeared that most women in this study contracted HSV-2 from their spouses and few regularly used condoms. This finding highlights the need for public health policies to increase awareness and education about prevention methods among women and men living in rural India.
目的。评估印度迈索尔县农村地区流动产前保健诊所就诊孕妇中单纯疱疹病毒2型（HSV - 2）感染的患病率及决定因素。方法。2009年1月至9月期间，来自52个村庄的487名妇女参与了本研究。每位参与者均同意提供血样进行HSV - 2和HIV检测，并接受访员管理的问卷调查。结果。HSV - 2患病率为6.7%（95%置信区间（CI）4.4 - 9.0），1名妇女HIV检测呈阳性。妇女的中位年龄为20岁，99%的妇女报告一生只有一个性伴侣。性伴侣离家外出的妇女HSV - 2血清学阳性的几率是性伴侣未外出妇女的2.68倍（CI：1.13 - 6.34）。有过生殖器病变也与HSV - 2感染有关（P值 = 0.08）。结论。6.7%的HSV - 2患病率与印度其他地区孕妇研究结果相似。本研究中大多数妇女似乎是从配偶那里感染HSV - 2的，很少有人经常使用避孕套。这一发现凸显了制定公共卫生政策以提高印度农村地区男女对预防方法的认识和教育的必要性。
