Division of Cardiothoracic Surgery, Joseph B. Whitehead Department of Surgery, Emory Structural Heart and Valve Center, Emory University Hospital and Emory University Hospital Midtown, Atlanta, Ga.
Department of Cardiology, Emory Structural Heart and Valve Center, Emory University Hospital and Emory University Hospital Midtown, Atlanta, Ga.
J Thorac Cardiovasc Surg. 2015 Oct;150(4):833-9. doi: 10.1016/j.jtcvs.2015.07.078. Epub 2015 Jul 30.
A minimalist approach for transcatheter aortic valve replacement (MA-TAVR) utilizing transfemoral access under conscious sedation and transthoracic echocardiography is increasing in popularity. This relatively novel technique may necessitate a learning period to achieve proficiency in performing a successful and safe procedure. This report evaluates our MA-TAVR cohort with specific characterization between our early, midterm, and recent experience.
We retrospectively reviewed 151 consecutive patients who underwent MA-TAVR with surgeons and interventionists equally as primary operator at Emory University between May 2012 and July 2014. Our institution had performed 300 TAVR procedures before implementation of MA-TAVR. Patient characteristics and early outcomes were compared using Valve Academic Research Consortium 2 definitions among 3 groups: group 1 included the first 50 patients, group 2 included patients 51 to 100, and group 3 included patients 101 to 151.
Median age for all patients was 84 years and similar among groups. The majority of patients were men (56%) and the median ejection fraction for all patients was 55% (interquartile range, 38.0%-60.0%). The majority of patients were high-risk surgical candidates with a median Society of Thoracic Surgeons Predicted Risk of Mortality of 10.0% and similar among groups. The overall major stroke rate was 3.3%, major vascular complications occurred in 3% of patients, and greater-than-mild paravalvular leak rate was 7%. In-hospital mortality and morbidity were similar among all 3 groups.
In a high-volume TAVR center, transition to MA-TAVR is feasible with acceptable outcomes and a diminutive procedural learning curve. We advocate for TAVR centers to actively pursue the minimalist technique with equal representation by cardiologists and surgeons.
经股动脉入路,在清醒镇静和经胸超声心动图引导下进行经导管主动脉瓣置换术(MA-TAVR)的简化方法越来越受欢迎。这种相对较新的技术可能需要一定的学习期,才能熟练掌握安全有效的手术操作。本研究报告评估了我们的 MA-TAVR 患者队列,特别关注了我们在早期、中期和近期经验之间的特征。
我们回顾性分析了 2012 年 5 月至 2014 年 7 月期间,在埃默里大学由外科医生和介入心脏病专家同等担任主要术者的 151 例连续 MA-TAVR 患者。在实施 MA-TAVR 之前,我们医院已经完成了 300 例 TAVR 手术。使用 Valve Academic Research Consortium 2 定义,根据 3 组患者的特征和早期结果进行比较:第 1 组包括前 50 例患者,第 2 组包括第 51 至 100 例患者,第 3 组包括第 101 至 151 例患者。
所有患者的中位年龄为 84 岁,且组间相似。大多数患者为男性(56%),所有患者的中位射血分数为 55%(四分位距,38.0%-60.0%)。大多数患者为高危外科手术候选者,中位胸外科医师协会预测死亡率为 10.0%,且组间相似。总的主要卒中发生率为 3.3%,3%的患者发生主要血管并发症,大于轻度瓣周漏发生率为 7%。所有 3 组的住院死亡率和发病率相似。
在高容量 TAVR 中心,向 MA-TAVR 的过渡是可行的,其结果可接受,手术学习曲线很小。我们主张 TAVR 中心积极采用微创技术,由心脏病专家和外科医生平等参与。