AlMakadma Hammam A, Henin Simon, Prieve Beth A, Dyab Walid M, Long Glenis R
Department of Communication Sciences and Disorders, Syracuse University, 621 Skytop Road, Suite 1200, Syracuse, NY 13210, United States.
Speech-Language-Hearing Sciences, Graduate School and University Center, City University of New York, 365 Fifth Avenue, NY 10016, United States.
Hear Res. 2015 Oct;328:157-65. doi: 10.1016/j.heares.2015.08.012. Epub 2015 Aug 28.
Distortion product otoacoustic emissions (DPOAE) in newborns and adults were evoked by sweeping primaries up and down in frequency at 1 s/octave. Sweeping up and down in frequency resulted in changes in the amplitude vs. frequency functions of the composite DPOAE and its two major components. In addition, DPOAE component phases differed slightly between the up- and down-swept conditions. The changes in amplitude vs. frequency functions were quantified using a covariate correlation technique, yielding single-valued estimates of the magnitude of the frequency changes. Separate analyses were performed for the entire DPOAE frequency range and split into low and high frequency ranges. There were consistent changes in newborn and adult composite DPOAEs and reflection components, but not generator components. Adults had significant frequency changes in the composite DPOAE for all frequency ranges and in the reflection component for the entire frequency range. Newborns had significant frequency change in the reflection component for all frequency ranges. Differences in frequency change between adults and newborns may stem from developmental changes in cochlear processing. Alignment of the component phase differences between the up- and down-swept conditions resulted in elimination of frequency-change in reconstructed composite DPOAEs.
通过以1个倍频程/秒的频率上下扫频基频来诱发新生儿和成人的畸变产物耳声发射(DPOAE)。频率上下扫频导致复合DPOAE及其两个主要成分的幅度与频率函数发生变化。此外,在扫频上升和扫频下降条件下,DPOAE成分的相位略有不同。使用协变量相关技术对幅度与频率函数的变化进行量化,得出频率变化幅度的单值估计。对整个DPOAE频率范围进行了单独分析,并分为低频和高频范围。新生儿和成人的复合DPOAE及反射成分存在一致的变化,但发生器成分没有。成人在所有频率范围内的复合DPOAE以及整个频率范围内的反射成分都有显著的频率变化。新生儿在所有频率范围内的反射成分都有显著的频率变化。成人与新生儿之间频率变化的差异可能源于耳蜗处理过程中的发育变化。扫频上升和扫频下降条件下成分相位差的对齐导致重建的复合DPOAE中频率变化的消除。