Kraus V B, Kilfoil T M, Hash T W, McDaniel G, Renner J B, Carrino J A, Adams S
Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA; Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Division of Rheumatology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA.
Osteoarthritis Cartilage. 2015 Dec;23(12):2059-2085. doi: 10.1016/j.joca.2015.08.008. Epub 2015 Aug 28.
To develop a radiographic atlas of osteoarthritis (OA) for use as a template and guide for standardized scoring of radiographic features of OA of the ankle and hindfoot joints.
Under Institutional Review Board approval, ankle and hindfoot images were selected from a cohort study and from among cases that underwent ankle radiography during a 6-month period at Duke University Medical Center. Missing OA pathology was obtained through supplementation of cases with the assistance of a foot and ankle specialist in Orthopaedic surgery and a musculoskeletal radiologist. Images were obtained and reviewed without patient identifying information. Images went through multiple rounds of review and final images were selected by consensus of the study team. For intra-rater and inter-rater reliability, the kappa statistic was calculated for two readings by three musculoskeletal radiologists, a minimum of two weeks apart, of ankle and hindfoot radiographs from 30 anonymized subjects.
The atlas demonstrates individual radiographic features (osteophyte and joint space narrowing (JSN)) and Kellgren-Lawrence grade for all aspects of the talocrural (ankle joint proper) and talocalcaneal (subtalar) joints. Reliability of scoring based on the atlas was quite good to excellent for most features indicated. Additional examples of ankle joint findings are illustrated including sclerosis, os trigonum, subchondral cysts and talar tilt.
It is anticipated that this atlas will assist with standardization of scoring of ankle and hindfoot OA by basic and clinical OA researchers.
编制骨关节炎(OA)的影像学图谱,作为踝关节和后足关节OA影像学特征标准化评分的模板和指南。
在机构审查委员会批准下,从一项队列研究以及杜克大学医学中心6个月期间接受踝关节X线摄影的病例中选取踝关节和后足图像。通过一名足踝外科骨科专家和一名肌肉骨骼放射科医生协助补充病例,获取缺失的OA病理信息。在不包含患者识别信息的情况下获取并审查图像。图像经过多轮审查,最终图像由研究团队达成共识选定。为评估评分者内和评分者间的可靠性,计算了三名肌肉骨骼放射科医生对30名匿名受试者的踝关节和后足X线片进行的两次读片的kappa统计量,两次读片间隔至少两周。
该图谱展示了胫距(踝关节本身)和距跟(距下)关节各方面的个体影像学特征(骨赘和关节间隙变窄(JSN))以及Kellgren-Lawrence分级。对于所指出的大多数特征,基于该图谱的评分可靠性相当好至优秀。还展示了踝关节其他发现的示例,包括硬化、三角骨、软骨下囊肿和距骨倾斜。
预计该图谱将有助于基础和临床OA研究人员对踝关节和后足OA评分的标准化。