Khataee Alireza, Lotfi Roya, Hasanzadeh Aliyeh, Iranifam Mortaza, Zarei Mahmoud, Joo Sang Woo
Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran.
Research Laboratory of Advanced Water and Wastewater Treatment Processes, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, 51666-16471 Tabriz, Iran.
Spectrochim Acta A Mol Biomol Spectrosc. 2016 Jan 15;153:273-80. doi: 10.1016/j.saa.2015.08.036. Epub 2015 Aug 22.
Two analytical approaches including chemiluminescence (CL) and corona discharge ionization ion mobility spectrometry (CD-IMS) were developed for sensitive determination of selegiline (SG). We found that the CL intensity of the KMnO4-Na2S2O3 CL system was significantly enhanced in the presence of L-cysteine capped CdS quantum dots (QDs). A possible CL mechanism for this CL reaction is proposed. In the presence of SG, the enhanced CL system was inhibited. Based on this inhibition, a simple and sensitive flow-injection CL method was proposed for the determination of SG. Under optimum experimental conditions, the decreased CL intensity was proportional to SG concentration in the range of 0.01 to 30.0 mg L(-1). The detection limit (3σ) was 0.004 mg L(-1). Also, SG was determined using CD-IMS, and under optimum conditions of CD-IMS, calibration curves were linear in the range of 0.15 to 42.0 mg L(-1), with a detection limit (3σ) of 0.03 mg L(-1). The precision of the two methods was calculated by analyzing samples containing 5.0 mg L(-1) of SG (n=11). The relative standard deviations (RSDs%) of the flow-injection CL and CD-IMS methods are 2.17% and 3.83%, respectively. The proposed CL system exhibits a higher sensitivity and precision than the CD-IMS method for the determination of SG.
开发了两种分析方法，即化学发光（CL）法和电晕放电电离离子迁移谱（CD-IMS）法，用于灵敏测定司来吉兰（SG）。我们发现，在L-半胱氨酸包覆的硫化镉量子点（QDs）存在下，高锰酸钾-硫代硫酸钠CL体系的CL强度显著增强。提出了该CL反应可能的CL机理。在SG存在下，增强的CL体系受到抑制。基于这种抑制作用，提出了一种简单灵敏的流动注射CL法测定SG。在最佳实验条件下，CL强度的降低与0.01至30.0 mg L⁻¹范围内的SG浓度成正比。检测限（3σ）为0.004 mg L⁻¹。此外，使用CD-IMS测定SG，在CD-IMS的最佳条件下，校准曲线在0.15至42.0 mg L⁻¹范围内呈线性，检测限（3σ）为0.03 mg L⁻¹。通过分析含有5.0 mg L⁻¹ SG的样品（n = 11）计算两种方法的精密度。流动注射CL法和CD-IMS法的相对标准偏差（RSDs%）分别为2.17%和3.83%。所提出的CL体系在测定SG方面比CD-IMS法具有更高的灵敏度和精密度。
