Ibrahim El-Sayed H, Cernigliaro Joseph G, Pooley Robert A, Williams James C, Haley William E
Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL, 32224, USA.
University of Michigan, 1500 E. Medical Center Dr., Ann Arbor, MI, 48109, USA.
Abdom Imaging. 2015 Oct;40(8):3161-7. doi: 10.1007/s00261-015-0530-9.
Dual-energy computed tomography (DECT) has shown the capability of differentiating uric acid (UA) from non-UA stones with 90-100% accuracy. With the invention of dual-source (DS) scanners, both low- and high-energy images are acquired simultaneously. However, DECT can also be performed by sequential acquisition of both images on single-source (SS) scanners. The objective of this study is to investigate the effects of motion artifacts on stone classification using both SS-DECT and DS-DECT.
114 kidney stones of different types and sizes were imaged on both DS-DECT and SS-DECT scanners with tube voltages of 80 and 140 kVp with and without induced motion. Postprocessing was conducted to create material-specific images from corresponding low- and high-energy images. The dual-energy ratio (DER) and stone material were determined and compared among different scans.
For the motionless scans, all stones were correctly classified with SS-DECT, while two cystine stones were misclassified with DS-DECT. When motion was induced, 94% of the stones were misclassified with SS-DECT versus 11% with DS-DECT (P < 0.0001). Stone size was not a factor in stone misclassification under motion. Stone type was not a factor in stone misclassification under motion with SS-DECT, although with DS-DECT, cystine showed higher number of stone misclassification.
Motion artifacts could result in stone misclassification in DECT. This effect is more pronounced in SS-DECT versus DS-DECT, especially if stones of different types lie in close proximity to each other. Further, possible misinterpretation of the number of stones (i.e., missing one, or thinking that there are two) in DS-DECT could be a potentially significant problem.
双能计算机断层扫描(DECT)已显示出以90 - 100%的准确率区分尿酸(UA)结石与非UA结石的能力。随着双源(DS)扫描仪的发明,低能和高能图像可同时获取。然而,DECT也可通过在单源(SS)扫描仪上顺序采集两幅图像来进行。本研究的目的是探讨运动伪影对使用SS - DECT和DS - DECT进行结石分类的影响。
114颗不同类型和大小的肾结石在DS - DECT和SS - DECT扫描仪上成像,管电压为80和140 kVp,有或无诱导运动。进行后处理以从相应的低能和高能图像创建特定物质图像。确定并比较不同扫描中的双能比(DER)和结石物质。
对于静止扫描,SS - DECT能正确分类所有结石,而DS - DECT将两颗胱氨酸结石误分类。当诱导运动时,SS - DECT对94%的结石误分类,而DS - DECT为11%(P < 0.0001)。结石大小不是运动状态下结石误分类的因素。在SS - DECT运动状态下,结石类型不是结石误分类的因素,尽管在DS - DECT中,胱氨酸结石的误分类数量较多。
运动伪影可导致DECT中结石误分类。这种影响在SS - DECT中比DS - DECT更明显,特别是如果不同类型的结石彼此紧邻。此外,DS - DECT中结石数量可能的错误解读(即漏诊一颗或误认为有两颗)可能是一个潜在的重大问题。