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发育过程中暴露于环境毒物

Developmental Exposure to Environmental Toxicants.

作者信息

Falck Alison J, Mooney Sandra, Kapoor Shiv S, White Kimberly M R, Bearer Cynthia, El Metwally Dina

机构信息

Department of Pediatrics, Division of Neonatology, University of Maryland School of Medicine, 110 South Paca Street, 8th Floor, Baltimore, MD 21201, USA.

Department of Pediatrics, Division of Neonatology, University of Maryland School of Medicine, 110 South Paca Street, 8th Floor, Baltimore, MD 21201, USA.

出版信息

Pediatr Clin North Am. 2015 Oct;62(5):1173-97. doi: 10.1016/j.pcl.2015.05.005. Epub 2015 Jul 26.

Abstract

Children interact with the physical environment differently than adults, and are uniquely susceptible to environmental toxicants. Routes of absorption, distribution, metabolism, and target organ toxicities vary as children grow and develop. This article summarizes the sources of exposure and known adverse effects of toxicants that are ubiquitous in our environment, including tobacco smoke, ethanol, solvents, heavy metals, volatile organic compounds, persistent organic pollutants, and pesticides. Preventive strategies that may be used in counseling children and their families are highlighted.

摘要

儿童与物理环境的互动方式不同于成人,并且对环境毒物具有独特的易感性。随着儿童的成长和发育,吸收、分布、代谢途径以及靶器官毒性都会有所不同。本文总结了我们环境中普遍存在的毒物的暴露源和已知的不良影响,包括烟草烟雾、乙醇、溶剂、重金属、挥发性有机化合物、持久性有机污染物和农药。文中强调了在为儿童及其家庭提供咨询时可能会用到的预防策略。

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