Hartig Dave, Waluga Thomas, Scholl Stephan
Technische Universität Braunschweig, Institute for Chemical and Thermal Process Engineering, Langer Kamp 7, D-38106 Braunschweig, Germany.
Technische Universität Braunschweig, Institute for Chemical and Thermal Process Engineering, Langer Kamp 7, D-38106 Braunschweig, Germany.
J Chromatogr A. 2015 Sep 25;1413:77-84. doi: 10.1016/j.chroma.2015.08.024. Epub 2015 Aug 15.
The elution by characteristic point (ECP) method provides a rapid approach to determine whole isotherm data with small material usage. It is especially desired wherever the adsorbent or the adsorbate is expensive, toxic or only available in small amounts. However, the ECP method is limited to adsorbents that are well optimized for chromatographic use and therefore provide a high number of theoretical plates when packed into columns (2000 or more for Langmuir type isotherms are suggested). Here we present a novel approach that uses a new profile correction to apply the ECP method to poorly optimized adsorbents with less than 200 theoretical plates. Non-ideality effects are determined using a dead volume marker injection and the resulting marker profile is used to compensate the named effects considering their dependency from the actual concentration instead of assuming rectangular profiles. Experimental and literature data are used to compare the new ECP approach with batch method results.
特征点洗脱（ECP）法提供了一种快速测定全等温线数据的方法，且材料用量少。在吸附剂或被吸附物昂贵、有毒或数量有限的任何情况下，这种方法尤其适用。然而，ECP法仅限于针对色谱用途进行了良好优化的吸附剂，因此装入色谱柱时能提供大量理论塔板（对于朗缪尔型等温线，建议为2000或更多）。在此，我们提出一种新方法，该方法使用新的谱图校正，将ECP法应用于理论塔板数少于200的未充分优化的吸附剂。使用死体积标记物进样来确定非理想效应，并根据标记物谱图对实际浓度的依赖性而非假设为矩形谱图来补偿上述效应。利用实验数据和文献数据将新的ECP方法与分批法结果进行比较。
