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经皮电刺激神经疗法(TENS)对深部子宫内膜异位症女性的辅助疼痛治疗效果:随机对照试验

Effectiveness of complementary pain treatment for women with deep endometriosis through Transcutaneous Electrical Nerve Stimulation (TENS): randomized controlled trial.

作者信息

Mira Ticiana A A, Giraldo Paulo C, Yela Daniela A, Benetti-Pinto Cristina L

机构信息

Department of Obstetrics and Gynecology, University of Campinas, Campinas, Brazil.

Department of Obstetrics and Gynecology, University of Campinas, Campinas, Brazil.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2015 Nov;194:1-6. doi: 10.1016/j.ejogrb.2015.07.009. Epub 2015 Aug 6.

DOI:10.1016/j.ejogrb.2015.07.009
PMID:26319650
Abstract

OBJECTIVE

Evaluate TENS effectiveness as a complementary treatment of chronic pelvic pain and deep dyspareunia in women with deep endometriosis.

STUDY DESIGN

This randomized controlled trial was performed in a tertiary health care center, including twenty-two women with deep endometriosis undergoing hormone therapy with persistent pelvic pain and/or deep dyspareunia. This study was registered in the Brazilian Record of Clinical Trials (ReBEC), under n RBR-3rndh6. TENS application for 8 weeks followed a randomized allocation into two groups: Group 1 - acupuncture-like TENS (Frequency: 8Hz, pulse duration: 250μs) - VIF (n=11) and Group 2 - self-applied TENS (Frequency: 85Hz, pulse duration: 75μs) (n=11). The intensity applied was "strong, but comfortable". We evaluated patients before and after treatment by the use of the Visual Analogue Scale, Deep Dyspareunia Scale and Endometriosis Quality of Life Questionnaire. We used the Wilcoxon and Mann-Whitney tests to compare before and after treatment conditions.

RESULTS

Despite the use of hormone therapy for 1.65±2.08 years, the 22 women with deep endometriosis sustained pelvic pain complaints (VAS=5.95±2.13 and 2.45±2.42, p<.001) and/or deep dyspareunia (DDS=2.29±0.46 and 1.20±1.01, p=.001). We observed significant improvement for chronic pelvic pain, deep dyspareunia and quality of life by the use of TENS. Both application types of TENS were effective for improving the evaluated types of pain.

CONCLUSIONS

Both resources (acupuncture-like TENS and self-applied TENS) demonstrated effectiveness as a complementary treatment of pelvic pain and deep dyspareunia, improving quality of life in women with deep endometriosis regardless of the device used for treatment.

摘要

目的

评估经皮电刺激神经疗法(TENS)作为深部子宫内膜异位症女性慢性盆腔疼痛和深部性交困难辅助治疗方法的有效性。

研究设计

这项随机对照试验在一家三级医疗保健中心进行,纳入了22名患有深部子宫内膜异位症且接受激素治疗后仍有持续性盆腔疼痛和/或深部性交困难的女性。本研究已在巴西临床试验注册系统(ReBEC)注册,注册号为RBR-3rndh6。TENS治疗8周,随机分为两组:第1组——类针刺TENS(频率:8Hz,脉冲持续时间:250μs)——VIF(n = 11);第2组——自我应用TENS(频率:85Hz,脉冲持续时间:75μs)(n = 11)。施加的强度为“强烈但舒适”。我们通过视觉模拟量表、深部性交困难量表和子宫内膜异位症生活质量问卷对患者治疗前后进行评估。我们使用Wilcoxon检验和Mann-Whitney检验比较治疗前后的情况。

结果

尽管接受了1.65±2.08年的激素治疗,但这22名深部子宫内膜异位症女性仍有盆腔疼痛主诉(视觉模拟量表评分分别为5.95±2.13和2.45±2.42,p <.001)和/或深部性交困难(深部性交困难量表评分分别为2.29±0.46和1.20±1.01,p =.001)。我们观察到使用TENS后慢性盆腔疼痛、深部性交困难和生活质量有显著改善。两种TENS应用类型对改善所评估的疼痛类型均有效。

结论

两种方法(类针刺TENS和自我应用TENS)均显示出作为盆腔疼痛和深部性交困难辅助治疗方法的有效性,可改善深部子宫内膜异位症女性的生活质量,无论使用何种治疗设备。

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