溴乙丁酰胺（卡溴脲）的心脏毒性（作者译）
[Cardiotoxicity of bromethylbutyramide (carbromide) (author's transl)].
作者信息
Strubelt O
出版信息
Arch Toxicol. 1978 Apr 27;40(2):151-4. doi: 10.1007/BF01891970.
PMID:26320
Abstract
Bromethylbutyramide (Carbromide), a quantitatively important metabolite of carbromal, diminished the contractility of electrically driven and the frequency of spontaneously beating guinea-pig atria. The negative inotropic action of bromethylbutyramide occurred at concentrations which are reached in human carbromal poisoning. The cardiodepressive actions of bromethylbutyramide and carbromal may be important for the course and the ending of severe carbromal intoxications.
摘要
溴乙丁酰胺（溴化碳酰）是溴米那的一种在数量上重要的代谢产物，它可降低电驱动的豚鼠心房的收缩力以及自发搏动的频率。溴乙丁酰胺的负性肌力作用发生在人体溴米那中毒时所能达到的浓度。溴乙丁酰胺和溴米那的心脏抑制作用可能对严重溴米那中毒的病程和结局具有重要意义。
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[Clinical features and treatment of carbromal poisoning].[溴米那中毒的临床特征与治疗]
Dtsch Med Wochenschr. 1972 Dec 8;97(49):1911-6. doi: 10.1055/s-0028-1107675.
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Actions of antiarrhythmic drugs on refractory period and contractility of isolated rat and guinea-pig atria.抗心律失常药物对离体大鼠和豚鼠心房不应期及收缩性的作用
Naunyn Schmiedebergs Arch Pharmakol. 1971;271(4):335-45. doi: 10.1007/BF00997123.
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[The clinical course of severe carbromal poisoning (author's transl)].重度溴米索伐中毒的临床病程（作者译）
Klin Wochenschr. 1974 Jan 1;52(1):39-49. doi: 10.1007/BF01468521.
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[On the toxicology of carbromal. I. Estimation of carbromal and its hypnotically active metabolites in rats and humans (author's transl)].[关于溴米那的毒理学。I. 大鼠和人体中溴米那及其催眠活性代谢物的测定（作者译）]
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