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[心脏手术候选者中的贫血]

[Anemia in candidates for heart surgery].

作者信息

Yanes Vidal G J

机构信息

Servicio de Anestesiología y Reanimación, Hospital Universitario Virgen del Rocío, Sevilla, España.

出版信息

Rev Esp Anestesiol Reanim. 2015 Jun;62 Suppl 1:69-75. doi: 10.1016/S0034-9356(15)30011-6.

Abstract

Heart surgery patients have a high prevalence of anemia. Its etiology is multifactorial, and iron deficiency is one of the most common correctable causes. Anemia is an independent risk factor for postsurgical morbidity and mortality. It also predisposes patients to a greater need for transfusions, which increases the associated complications and the use of resources. The etiological diagnosis of anemia is no different from that of other surgical procedures, but the time available for correcting it before surgery is shorter. Studies have been conducted on therapeutic regimens with iron deficiency replenishment with total dose and erythropoiesis-stimulating agents, which enable the rapid correction of anemia and reduce transfusion requirements. There is considerable variability in terms of dosage, adverse effects, administration time and routes, drug combinations and results. New studies are needed to investigate the most ideal regimens for correcting anemia in these patients.

摘要

心脏手术患者贫血的患病率很高。其病因是多因素的,缺铁是最常见的可纠正病因之一。贫血是术后发病和死亡的独立危险因素。它还使患者更需要输血,这增加了相关并发症和资源的使用。贫血的病因诊断与其他外科手术无异,但术前纠正贫血的可用时间较短。已经对补充铁剂总量和促红细胞生成剂的治疗方案进行了研究,这些方案能够快速纠正贫血并减少输血需求。在剂量、不良反应、给药时间和途径、药物组合及结果方面存在很大差异。需要开展新的研究来探究纠正这些患者贫血的最理想方案。

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