Axelsen Tobias Melton, Navntoft Charlotte Amalie Emdal, Christiansen Søren Hofman, Dreyer Jakob Kisbye, Sørensen Jakob Balslev, Gether Ulrik, Woldbye David Paul Drucker
Laboratorium for Neural Plasticitet, Institut for Neurovidenskab og Farmakologi, Københavns Universitet, Symbion, Fruebjergvej 3, 2100 København Ø.
Ugeskr Laeger. 2015 Aug 17;177(34).
Optogenetics is an emergent technology that combines light-sensitive proteins derived from algae, so-called opsins, with genetics. Viral vectors encoding opsins are injected into selective brain regions whereby specific cell populations can be controlled with high precision light pulses delivered via implanted optical fibres. This review focuses on explaining basic principles of optogenetics and describes important insights into neuropsychiatric mechanisms provided by the technology.
