Zhu Y Q, Liu J J, Tao Z
Zhonghua Nei Ke Za Zhi. 1989 Nov;28(11):667-9, 701.
Embolization of bleeding gastroesophageal varices with absolute ethanol performed in the recent two years was reported. The treatment was carried out either by means of percutaneous transhepatic or transileocolic obliteration. Obliteration treatment was attempted in 42 cases, among which 20 were transhepatic and 22 transileocolic. 16 of the 20 and 17 of the 22 were effectively obliterated with a total success rate of 78.6%. Two control groups of bleeding varices, one of 45 cases treated with conventional medical methods and the other of 53 cases treated with endoscopic sclerotherapy, were studied to compare the results. The efficacy for control of active bleeding in the obliteration, conventional and sclerotherapy groups were 100%, 84.1%, and 91% respectively, while the rebleeding rate was 27.2%, 31.5% and 23.2% and mortality rate (due to rebleeding) 12.1%, 31.5% and 11.6% respectively. The control of active bleeding, the results in the three groups were more or less similar, but the rebleeding rate was much lower in the obliteration and sclerotherapy groups than in the conventional group. However, sclerotherapy requires longer time and yields more complications than obliteration is a valuable therapeutic measure in controlling variceal bleeding and preventing rebleeding.
报道了近两年用无水乙醇栓塞治疗出血性胃食管静脉曲张的情况。治疗通过经皮经肝或经回结肠闭塞术进行。对42例患者尝试了闭塞治疗，其中20例采用经肝途径，22例采用经回结肠途径。20例中的16例和22例中的17例有效闭塞，总成功率为78.6%。研究了两个出血性静脉曲张对照组，一组45例采用传统药物治疗，另一组53例采用内镜硬化疗法，以比较结果。闭塞组、传统治疗组和硬化疗法组控制活动性出血的有效率分别为100%、84.1%和91%，而再出血率分别为27.2%、31.5%和23.2%，死亡率（因再出血）分别为12.1%、31.5%和11.6%。三组在控制活动性出血方面结果大致相似，但闭塞组和硬化疗法组的再出血率远低于传统治疗组。然而，硬化疗法比闭塞术所需时间更长且并发症更多，闭塞术是控制静脉曲张出血和预防再出血的一种有价值的治疗措施。
