Rahman Tabishur, Ahmed Syed S, Khan Harris M, Hashmi Ghulam S, Rahman Sajjad A, Ansari Kalim M
Department of Oral and Maxillofacial Surgery, Dr. Ziauddin Ahmed Dental College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Department of Microbiology, Surgery Aligarh Muslim University Jawaharlal Nehru medical College and Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Contemp Clin Dent. 2015 Jul-Sep;6(3):405-8. doi: 10.4103/0976-237X.161903.
The purpose of this study is to compare the efficiency of culture methods in detecting microorganisms appearing in the bloodstream after various oral surgical procedures and effect of preoperative antibiotics and antiseptic rinses on bacteremia.
The prevalence of bacteremia at various intervals of time (pre- and post-surgical) was studied in three different groups presenting with indications to surgical intervention. Two of the groups were given presurgical prophylaxis (systemic antibiotic and antiseptic rinse) while, in one group, no prophylactic measure was adopted. Blood samples were withdrawn from the subjects at specific pre- and post-surgical time intervals, and microbiological analysis was done. The findings were compared with a control group involving healthy individuals and a group involved in maxillofacial trauma where the breach of oral mucosal integrity was not surgically planned.
The presence of bacteremia was not observed in all five groups at baseline while postsurgery (30 min, 60 min, and 90 min) in only three groups (preoperative antibiotic, without prophylaxis, and 1% Povidone iodine rinse). At all postsurgery periods (30 min, 60 min and 90 min), the presence of bacteremia was evident highest in without prophylaxis group followed by 1% Povidone iodine rinse and preoperative antibiotic the least.
本研究的目的是比较培养方法在检测各种口腔外科手术后出现在血液中的微生物的效率,以及术前使用抗生素和抗菌漱口水对菌血症的影响。
在三组有手术干预指征的患者中,研究了不同时间间隔(术前和术后)菌血症的发生率。其中两组在术前接受了预防措施(全身使用抗生素和抗菌漱口水),而另一组未采取任何预防措施。在特定的术前和术后时间间隔从受试者采集血样,并进行微生物分析。将研究结果与一个包含健康个体的对照组以及一个涉及颌面部创伤但未计划进行手术破坏口腔黏膜完整性的组进行比较。
在基线时,所有五组均未观察到菌血症,而术后(30分钟、60分钟和90分钟)仅在三组中观察到菌血症(术前使用抗生素组、未采取预防措施组和1%聚维酮碘漱口水组)。在所有术后时间段(30分钟、60分钟和90分钟),未采取预防措施组菌血症的发生率明显最高,其次是1%聚维酮碘漱口水组,术前使用抗生素组最低。