Honda T, Morinaga J, Ohoh K, Tsuboi K, Mochizuki A, Komoto K
Fukuoka Shika Daigaku Gakkai Zasshi. 1989;16(1):70-6.
A case of carcinoma of the tongue treated with neoadjuvant chemotherapy has been reported. The patient was a 61-year-old man complaining of tumor and contact pain at the left margin of the tongue. The tumor was oval and elastic soft with pedicle, measuring 26 X 16 X 8 mm in size. The tumor was histopathologically diagnosed as a highly differentiated squamous cell carcinoma. The patient was treated with CDDP (75 mg/body) and PEP (5 mg/body) for 5 days. After two trials with about a 3-week interval, treatment result showed partial response. This result demonstrated that combination chemotherapy of CDDP and PEP is an effective regimen for remission neoadjuvant chemotherapy in patients with squamous cell carcinoma.
据报道，有一例舌癌患者接受了新辅助化疗。该患者为一名61岁男性，主诉舌左侧边缘有肿物及接触性疼痛。肿物呈椭圆形，质地有弹性，柔软，有蒂，大小为26×16×8毫米。该肿物经组织病理学诊断为高分化鳞状细胞癌。患者接受顺铂（75毫克/体）和表柔比星（5毫克/体）治疗5天。在间隔约3周进行了两个疗程的治疗后，治疗结果显示部分缓解。该结果表明，顺铂和表柔比星联合化疗是鳞状细胞癌患者新辅助化疗缓解的有效方案。
