Leiderman Eduardo A, Lorenzo Laura
Vertex. 2015 Jan-Feb;26(119):11-6.
The aim of this study was to determine prescribing patterns for the pharmacological treatment of schizophrenia in a sample of Argentinean psychiatrists and to compare some results with those obtained in a previous survey done on a similar population.
A self-administered survey was conducted among psychiatrists who attended a conference of psychopharmacology held in August 2012 in Buenos Aires city. Answers were analyzed descriptively and some of them were compared with results of another survey done in 2006 in a psychiatry conference.
Ninety six percent of the surveyed psychiatrists considered that every schizophrenic patient with an acute episode must be pharmacologically treated. For the acute and chronic treatment of positive symptoms most psychiatrists chose risperidone, haloperidol, olanzapine and quetiapine. In contrast, for the chronic treatment of negative symptomatology, physicians preferred risperidone, aripiprazole, olanzapine, quetiapine and clozapine. An increased choice of quetiapine and aripiprazole was observed between this survey and the previous one. Sixty four percent of respondents reported using antipsychotic combination, similar as assessed in the previous survey. Most preferred to maintain pharmacological treatment during the pregnancy, although changing the antipsychotic to haloperidol. Ninety eight percent stated that they use some kind of psychotherapy in the treatment.
In the pharmacological treatment of schizophrenia, similarities between reported clinical practice and current treatment guidelines were observed. There were no significant differences in the prescription patterns referred by psychiatrists between 2006 and 2012.
本研究旨在确定阿根廷精神科医生样本中精神分裂症药物治疗的处方模式，并将一些结果与之前对类似人群进行的调查结果进行比较。
对参加2012年8月在布宜诺斯艾利斯市举行的精神药理学会议的精神科医生进行了一项自填式调查。对答案进行了描述性分析，并将其中一些与2006年在一次精神病学会议上进行的另一项调查结果进行了比较。
96%的受访精神科医生认为，每一位患有急性发作的精神分裂症患者都必须接受药物治疗。对于阳性症状的急性和慢性治疗，大多数精神科医生选择利培酮、氟哌啶醇、奥氮平和喹硫平。相比之下，对于阴性症状的慢性治疗，医生们更喜欢利培酮、阿立哌唑、奥氮平、喹硫平和氯氮平。与前一次调查相比，本次调查中喹硫平和阿立哌唑的选择有所增加。64%的受访者报告使用抗精神病药物联合治疗，与前一次调查评估的情况相似。大多数人倾向于在怀孕期间维持药物治疗，尽管会将抗精神病药物换成氟哌啶醇。98%的人表示他们在治疗中使用某种心理治疗。
在精神分裂症的药物治疗中，观察到报告的临床实践与当前治疗指南之间存在相似之处。2006年至2012年期间，精神科医生提及的处方模式没有显著差异。
